Stanley F J, Burgar P J, Fong N W, Milroy H M
Aust Paediatr J. 1985 May;21(2):111-4. doi: 10.1111/j.1440-1754.1985.tb00139.x.
The birth prevalence of congenital rubella syndrome (CRS) in Western Australia has been around 20 per 10 000 live births with peaks up to 100 per 10 000 in rubella epidemic years. The rate appears to be falling but it is still too soon to know whether the rubella vaccination programme in Western Australia has made a significant impact. The cohorts of young women who would have received the schoolgirl vaccination programme are only now entering the child bearing age groups. Observed falls may be due also to delayed diagnosis particularly of cases of deafness only. The proportion of nonimmune young women who would have been eligible for the programme in one maternity hospital has fallen. This study needs to be repeated to ascertain whether further epidemics of rubella have resulted in peaks of CRS or whether the vaccination programme has started to have an effect.
西澳大利亚先天性风疹综合征(CRS)的出生患病率约为每10000例活产中有20例,在风疹流行年份峰值可达每10000例中有100例。该比率似乎在下降,但现在判断西澳大利亚的风疹疫苗接种计划是否产生了显著影响还为时过早。原本应接受在校女生疫苗接种计划的年轻女性群体才刚刚进入育龄期。观察到的下降情况也可能归因于诊断延迟,尤其是仅针对耳聋病例的诊断延迟。在一家妇产医院,符合该计划接种条件的未免疫年轻女性的比例有所下降。需要重复这项研究,以确定风疹的进一步流行是否导致了CRS的峰值,或者疫苗接种计划是否已开始产生效果。