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腮腺基底细胞腺瘤的外科治疗:一例报告并文献复习

Surgical management of basal cell adenoma of the parotid gland: A case report and review of the literature.

作者信息

Nnko Kanankira A, Pima Raphael T, Mremi Alex

机构信息

Department of Dentistry, Kilimanjaro Christian Medical Centre, Moshi, Tanzania; Faculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Department of Dentistry, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

出版信息

Int J Surg Case Rep. 2024 Nov;124:110434. doi: 10.1016/j.ijscr.2024.110434. Epub 2024 Oct 10.

Abstract

INTRODUCTION AND IMPORTANCE

Basal cell adenoma (BCA) is a rare, benign tumor of the salivary gland. It has distinct histologic features that are different from mixed tumors of the salivary gland. Often times, it occurs in the parotid gland. Usually it appears as a hard, slowly growing, asymptomatic lump that may exist for years prior to treatment. Pathologically, BCA tumors demonstrate a monomorphic basaloid cell population devoid of myxochondroid components. This rather uncommon tumor's clinical appearance, pathological characteristics, differential diagnosis, and available treatments have been briefly described.

CASE PRESENTATION

A 52-year-old female patient presented with a longstanding, gradual facial asymmetry that resulted from a mass of parotid region. She had no other symptoms. Radiology and cytology test results were suggestive of a benign salivary gland tumor of the parotid gland. A superficial parotidectomy was successfully done with a preservation of the facial nerve. Histopathology reported concluded the diagnosis of BCA trabecular subtype. During the 12-month follow-up period, the tumor did not recur, and there was no postoperative impairment of the facial nerve.

CLINICAL DISCUSSION

Imaging studies, including CT scans and MRI, are helpful in determining the tumor's size, location, and relationship to adjacent structures. The definitive diagnosis is achieved through histopathology. This clinically asymptomatic mass requires early recognition, a prompt therapeutic intervention and long-term follow-up.

CONCLUSION

As clinicians, it is critical that we have a thorough understanding of clinicopathology in terms of clinical presentation, pathology, diagnosis, treatment, and prognosis of this rare tumor.

摘要

引言与重要性

基底细胞腺瘤(BCA)是一种罕见的唾液腺良性肿瘤。它具有与唾液腺混合瘤不同的独特组织学特征。通常发生于腮腺。通常表现为质地坚硬、生长缓慢、无症状的肿块,在治疗前可能已存在数年。病理上,BCA肿瘤表现为单一的基底样细胞群,缺乏黏液软骨样成分。本文简要描述了这种相对不常见肿瘤的临床表现、病理特征、鉴别诊断及可用治疗方法。

病例介绍

一名52岁女性患者因腮腺区肿块导致长期渐进性面部不对称。她无其他症状。影像学和细胞学检查结果提示为腮腺良性唾液腺肿瘤。成功实施了保留面神经的腮腺浅叶切除术。组织病理学报告确诊为BCA小梁亚型。在12个月的随访期内,肿瘤未复发,面神经也无术后损伤。

临床讨论

包括CT扫描和MRI在内的影像学检查有助于确定肿瘤的大小、位置以及与相邻结构的关系。通过组织病理学可实现明确诊断。这种临床无症状的肿块需要早期识别、及时的治疗干预和长期随访。

结论

作为临床医生,我们必须全面了解这种罕见肿瘤在临床表现、病理、诊断、治疗及预后方面的临床病理学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5003/11525116/6f7578e94e48/gr1.jpg

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