Collado-Murcia Yolanda, Parra-Perez Francisco, López-Jornet Pia
Department of Dermatology, Stomatology, Radiology and Physical Medicine, Faculty of Medicine, University of Murcia, Hospital Morales Meseguer Clinica Odontologica Marques Velez S/N, 30008 Murcia, Spain.
J Clin Med. 2024 Sep 25;13(19):5709. doi: 10.3390/jcm13195709.
: Photobiomodulation (PBM) is a non-invasive procedure used to manage pain and inflammation. The aim of this study is to quantitatively measure pain and inflammation and to compare the proposed PBM treatment with a simulated treatment (PBM-SHAM) in patients with dental implants. : A total of 62 patients were included and randomized into two groups. Group 1 (PBM) consisted of 31 patients subjected to the insertion of dental implants and a single intraoral PBM session with an EPIC X Biolase (0.5 W and 15 J/cm²) diode laser. Group II (PBM-SHAM) included 31 patients subjected to dental implants and a simulated PBM. Each patient was given a document with visual analog scales (VASs) to record pain and inflammation during the 7 days post-surgery. The patients were assessed at the end of the week to remove the sutures, to collect the VASs, and to re-evaluate the surveys. : Through the use of mixed effects models, it was found that the length of time after the surgery and the number of implants placed during the intervention were important variables that had an influence on pain and inflammation. : PBM is a non-invasive and safe treatment. Postoperative pain and inflammation associated with implant surgery decreased in a similar manner over time, independently of the application of PBM. Therefore, more randomized studies are needed with a standardized methodology to adequately assess the efficacy of this therapy.
光生物调节疗法（PBM）是一种用于控制疼痛和炎症的非侵入性治疗方法。本研究的目的是定量测量疼痛和炎症，并比较在牙种植体患者中所提议的PBM治疗与模拟治疗（PBM-假手术）的效果。
总共纳入了62例患者，并随机分为两组。第1组（PBM组）由31例接受牙种植体植入手术并使用EPIC X Biolase（0.5瓦和15焦耳/平方厘米）二极管激光进行单次口腔内PBM治疗的患者组成。第2组（PBM-假手术组）包括31例接受牙种植体植入手术并接受模拟PBM治疗的患者。为每位患者提供一份带有视觉模拟量表（VAS）的文件，以记录术后7天内的疼痛和炎症情况。在术后一周结束时对患者进行评估，拆除缝线，收集VAS量表，并重新评估调查问卷。
通过使用混合效应模型发现，术后时间长度和干预期间植入的种植体数量是对疼痛和炎症有影响的重要变量。
PBM是一种非侵入性且安全的治疗方法。与种植体手术相关的术后疼痛和炎症随时间以相似的方式减轻，与PBM的应用无关。因此，需要更多采用标准化方法的随机研究来充分评估这种治疗方法的疗效。
