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低水平激光疗法在减少种植牙手术后疼痛方面的有效性:一项随机临床试验。

Effectiveness of Low-Level Laser Therapy in reducing postoperative pain after dental implant surgery: A randomized clinical trial.

机构信息

Departamento de Graduados, Facultad de Odontología, Universidad de Chile, Chile.

Restorative Dentistry Departament, Faculty of Dentistry, University of Chile.

出版信息

Photodiagnosis Photodyn Ther. 2024 Oct;49:104293. doi: 10.1016/j.pdpdt.2024.104293. Epub 2024 Aug 3.

DOI:10.1016/j.pdpdt.2024.104293
PMID:39098624
Abstract

BACKGROUND

A clinical trial was conducted to measure the effectiveness of a combined wavelength of 660 nm and 808 nm Low-Level Laser Therapy (LLLT) in reducing postoperative pain in partially and totally edentulous patients who underwent dental implant surgery.

MATERIALS AND METHODS

The study included 20 blinded individuals divided in a randomized split-mouth fashion; the experimental group in one hemiarch and the control group in the other hemiarch. The experimental group received a total of 22.5 Joules (J) of LLLT divided into 5 points per implant immediately after surgery. The control group received a placebo treatment. At 24 h, 72 h, and 7 days, a blinded surveyor administered a pain questionnaire using a Numerical Rating Scale (NRS) combined with a Verbal Rating Scale (VRS) to assess pain onset after surgery, duration of the first pain episode, and pain evolution. Group data were analyzed with an ANOVA test for repeated measures and a paired t-test at defined time intervals.

RESULTS

The experimental group showed a significant decrease in postoperative pain at 24 h and at 72 h for fully edentulous patients. There was a non-significant difference in the duration of the first pain episode. The mean pain levels decreased over time for both the experimental and control treatments, but only statistically significantly for the experimental group in the 24-72 h and 24 h to 7 days intervals. The same was true for the control group when comparing 24 and 72 h and between 24 h and 1 week. The time range between 72 h and 1 week showed no statistically significant differences.

CONCLUSION

Within the limitations of this study, a single dose of 22.5 J LLLT per implant helps to decrease postoperative pain in dental implant surgery at 24 h for partially edentulous patients and at 24 and 72 h for fully edentulous patients.

摘要

背景

一项临床试验旨在测量 660nm 和 808nm 双波长低水平激光疗法(LLLT)在减少部分和完全无牙患者接受牙种植手术后术后疼痛的效果。

材料与方法

本研究包括 20 名接受盲法分半设计的个体;实验组在半口,对照组在另半口。实验组每个种植体共接受 22.5 焦耳(J)的 LLLT,术后立即分为 5 点。对照组接受安慰剂治疗。在 24 小时、72 小时和 7 天时,一位盲法调查员使用数字评分量表(NRS)结合语言评分量表(VRS)对疼痛问卷进行评估,以评估手术后疼痛发作、首次疼痛发作持续时间和疼痛演变。组数据采用重复测量方差分析和特定时间间隔的配对 t 检验进行分析。

结果

完全无牙患者在术后 24 小时和 72 小时,实验组疼痛明显减轻。首次疼痛发作持续时间无显著差异。实验组和对照组的平均疼痛水平随时间降低,但仅在实验组 24-72 小时和 24 小时至 7 天间隔内具有统计学意义。对照组在比较 24 小时和 72 小时以及 24 小时和 1 周时也是如此。72 小时至 1 周之间的时间范围无统计学显著差异。

结论

在本研究的限制范围内,每个种植体单次 22.5 J 的 LLLT 有助于减少部分无牙患者在牙种植手术后 24 小时和完全无牙患者在 24 小时和 72 小时的术后疼痛。

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