Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Center for Innovation and Precision Dentistry (CiPD), School of Dental Medicine, School of Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Photobiomodul Photomed Laser Surg. 2023 Mar;41(3):93-103. doi: 10.1089/photob.2022.0161. Epub 2023 Feb 28.
This analysis was designed to present a summary of available evidence that will inform practice and guide future research for photobiomodulation (PBM) after titanium implant placement procedures. A systematic review was performed according to the Cochrane Collaboration and in line with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) criteria. Two investigators screened the titles and abstracts, and reviewed articles for risk of bias. Online databases searched included PubMed, Embase, Scopus, and Web of Science. Terms were specific to the effects of PBM on dental implant stability. Eight hundred fifty-six studies were identified, and 15 studies fulfilled the inclusion criteria. Light sources included both laser and light emitting diode (LED) devices. Wavelengths ranged from 618 to 1064 nm. The meta-analysis concluded that all 15 published studies were able to safely apply PBM near dental implants without adverse events. Laser and LED wavelengths that reported significant results included 618, 626, 830, 940 (2 × ), and 1064 nm. The use of adjunctive PBM can be safely prescribed after surgical placement of titanium implants. Six groups reported statistical significance for improving implant stability (four laser diode, two LED) in wavelengths ranging from 618 to 1064 nm. The amount of time spent delivering PBM was not a variable that differentiated whether a study reported significant results.
本分析旨在提供现有证据的总结，为光生物调节（PBM）在钛植入物放置手术后的实践提供信息，并指导未来的研究。根据 Cochrane 协作和系统评价和荟萃分析报告的首选项目（PRISMA）标准进行了系统评价。两名调查员筛选了标题和摘要，并对文章进行了偏倚风险评估。在线数据库搜索包括 PubMed、Embase、Scopus 和 Web of Science。术语专门针对 PBM 对牙科植入物稳定性的影响。确定了 856 项研究，其中 15 项研究符合纳入标准。光源包括激光和发光二极管（LED）设备。波长范围从 618 到 1064nm。荟萃分析得出结论，所有 15 项已发表的研究都能够在牙科植入物附近安全应用 PBM 而无不良事件。报告有显著结果的激光和 LED 波长包括 618、626、830、940（2×）和 1064nm。在钛植入物手术后，可以安全地使用辅助性 PBM。有六组报告了在 618 至 1064nm 波长范围内改善植入物稳定性（四个激光二极管，两个 LED）的统计学意义。给予 PBM 的时间长短并不是区分研究报告是否有显著结果的变量。
