Bodey Rochelle, Grimaldi Jennifer, Tait Hannah, Godfrey Belinda, Witton Sharon, Shardha Jenna, Tarrant Rachel, Sivan Manoj
Leeds Long COVID Community Rehabilitation Service, Leeds Community Healthcare NHS Trust, Leeds LS11 0DL, UK.
National Demonstration Centre of Rehabilitation Medicine, Leeds Teaching Hospitals NHS Trust, Leeds LS7 4SA, UK.
J Clin Med. 2024 Sep 29;13(19):5817. doi: 10.3390/jcm13195817.
Post COVID-19 syndrome or long COVID (LC) is a novel fluctuating condition with a protracted course in some patients. Specialist LC services have been operational in the UK since 2020 and deal with a high caseload of patients. To evaluate long-term outcomes in patients discharged from a community-based LC specialist service. A service evaluation study that included patients who were well engaged in the services [completed the standard Patient Reported Outcome Measures (PROMs) and received intervention from clinician(s)] and had been discharged for at least 3 months from the service. They consented to the study and completed standard PROMs: COVID-19 Yorkshire Rehabilitation Scale (C19-YRS), EQ-5D-5L and National Institute for Health and Care Excellence (NICE) criteria for myalgia encephalomyelitis/chronic fatigue syndrome (ME/CFS). Out of 460 patients contacted, 112 (average of 37.6 months since infection and 9.8 months post-discharge) completed the PROMs. Of these, 90.2% patients continued to experience LC symptoms and disability and had not returned to their pre-COVID-19 health status. The average EQ-5D-5L index score was 0.53 (SD 0.29), highlighting a significant disability and that LC had become a long-term condition (LTC) in the majority of patients who responded to the survey. Of these patients, 43% met the criteria for suspected ME/CFS. A proportion of LC patients develop persistent long COVID (PLC) consistent with a LTC and had a significant overlap with ME/CFS.
新冠后综合征或长新冠（LC）是一种新型的、症状波动的疾病，部分患者病程迁延。自2020年以来，英国已开展了专门的长新冠服务，接待了大量患者。为评估从社区长新冠专科服务机构出院患者的长期预后。这是一项服务评估研究，纳入了积极参与该服务的患者（完成了标准的患者报告结局量表（PROMs）并接受了临床医生的干预），且已从该服务机构出院至少3个月。他们同意参与研究并完成了标准的PROMs：新冠-约克郡康复量表（C19-YRS）、EQ-5D-5L以及英国国家卫生与临床优化研究所（NICE）制定的肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）标准。在联系的460名患者中，112名患者（感染后平均37.6个月，出院后平均9.8个月）完成了PROMs。其中，90.2%的患者仍有长新冠症状和残疾，尚未恢复到新冠前的健康状态。EQ-5D-5L指数平均得分为0.53（标准差0.29），突出表明存在严重残疾，且在大多数参与调查的患者中，长新冠已成为一种长期疾病（LTC）。在这些患者中，43%符合疑似ME/CFS的标准。一部分长新冠患者发展为持续性长新冠（PLC），符合长期疾病的特征，且与ME/CFS有显著重叠。
