犬存在慢性放射性改变时低位前切除术的安全性

Safety of low anterior resection in the presence of chronic radiation changes in dogs.

作者信息

Meese D L, Bubrick M P, Paulson G L, Feeney D A, Johnston G R, Strom R L, Hitchcock C R

出版信息

Dis Colon Rectum. 1986 Jan;29(1):22-6. doi: 10.1007/BF02555279.

Abstract

Thirty mongrel dogs underwent 4000- or 5000-rad single treatment orthovoltage irradiation to the pelvis according to the nominal standard dose equation. Following a resting period of six months, 21 dogs were randomized to low anterior resection with either stapled or handsewn anastomoses. Anastomotic leaks were evaluated on clinical and radiographic grounds. The radiographic leak rate was 81 percent for sutured and 0 percent for stapled anastomoses. The clinical leak rate was 18 percent for sutured and 0 percent for stapled anastomoses. The difference between the 4000- and 5000-rad groups was not significant. The data suggest that late effects of irradiation do not preclude the safe construction of low anterior anastomoses, and that the circular stapling device is superior to hand-sewn techniques.

摘要

根据标称标准剂量公式，对30只杂种犬的骨盆进行4000拉德或5000拉德的单次治疗正交电压照射。经过六个月的休息期后，将21只犬随机分为低位前切除术组，分别采用吻合器吻合或手工缝合。根据临床和影像学标准评估吻合口漏。缝合吻合的影像学漏率为81%，吻合器吻合的漏率为0%。缝合吻合的临床漏率为18%，吻合器吻合的漏率为0%。4000拉德组和5000拉德组之间的差异不显著。数据表明，照射的晚期效应并不妨碍低位前吻合术的安全实施，并且圆形吻合器优于手工缝合技术。