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泰国呵叻府2型糖尿病患者血糖控制的影响因素:一项分析性横断面研究

Factors Affecting Glycemic Control in Patients with Type 2 Diabetes in Kalasin Province, Thailand: An Analytical Cross-Sectional Study.

作者信息

Phuwilert Patcharin, Khiewkhern Santisith, Phajan Teerasak, Wongprachum Kasama, Wibuloutai Jindawan, Srichomphoo Chitkamon, Nghiep Le Ke, Tudpor Kukiat

机构信息

Faculty of Public Health, Mahasarakham University, Maha Sarakham 44150, Thailand.

Public Health and Environmental Policy in Southeast Asia Research Cluster (PHEP-SEA), Mahasarakham University, Maha Sarakham 44150, Thailand.

出版信息

Healthcare (Basel). 2024 Sep 25;12(19):1916. doi: 10.3390/healthcare12191916.

DOI:10.3390/healthcare12191916
PMID:39408096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11475190/
Abstract

Optimal glycemic management is critical since it can predict all associated essential causes of death, even after accounting for other risk factors. This study investigated the factors associated with glycemic control in patients with type 2 diabetes mellitus (T2DM), particularly self-care behaviors. An analytical cross-sectional study examined 385 patients with T2DM in 1 general and 17 community hospitals in Kalasin Province. The samples were collected using mixed-method sampling. Data were collected using a validated questionnaire with six parts and laboratory examination records between September 2021 and December 2022. Descriptive statistics (e.g., percentages and means ± SD) were used to analyze the data. The relationship between relevant factors and lack of glycemic control was analyzed by multivariate logistic regression using SPSS version 25. Results showed that most patients were female (78.18%), and the mean age was 59.84 ± 9.05 years. Additionally, a significant proportion of the patients (79.74%) had poor glycemic control. Several factors are significantly associated with poor glycemic control in patients with T2DM. These factors included subjects under the age of 60 years (OR = 2.95, 95% CI: 1.57 to 5.54; -value < 0.001), a diabetes duration of over 10 years (OR = 3.95, 95% CI: 1.90 to 8.22; -value < 0.001), poor knowledge about diabetes (OR = 3.92, 95% CI: 1.59 to 9.67; -value < 0.003), and inadequate self-care behaviors (OR = 6.12, 95% CI: 3.20 to 11.68; -value < 0.001). In conclusion, proper interventions for controlling glycemic level behaviors are necessary to improve proper self-care behaviors in patients who have a low knowledge level of T2DM, have had diabetes for over ten years, and are aged < 60 years. This approach can reduce the likelihood of experiencing disabilities and economic hardship.

摘要

最佳血糖管理至关重要,因为即便在考虑了其他风险因素之后,它仍能预测所有相关的主要死因。本研究调查了2型糖尿病(T2DM)患者血糖控制的相关因素,尤其是自我护理行为。一项分析性横断面研究对呵叻府1家综合医院和17家社区医院的385例T2DM患者进行了检查。样本采用混合方法抽样收集。在2021年9月至2022年12月期间,使用一份经过验证的包含六个部分的问卷和实验室检查记录收集数据。描述性统计(如百分比和均值±标准差)用于分析数据。使用SPSS 25版通过多因素逻辑回归分析相关因素与血糖控制不佳之间的关系。结果显示,大多数患者为女性(78.18%),平均年龄为59.84±9.05岁。此外,相当一部分患者(79.74%)血糖控制不佳。几个因素与T2DM患者血糖控制不佳显著相关。这些因素包括60岁以下的受试者(OR = 2.95,95%CI:1.57至5.54;P值<0.001)、糖尿病病程超过10年(OR = 3.95,95%CI:1.90至8.22;P值<0.001)、对糖尿病的认知较差(OR = 3.92,95%CI:1.59至9.67;P值<0.003)以及自我护理行为不足(OR = 6.12,95%CI:3.20至11.68;P值<0.001)。总之,对于T2DM知识水平较低、糖尿病病程超过十年且年龄<60岁的患者,采取适当干预措施以控制血糖水平行为对于改善其适当的自我护理行为是必要的。这种方法可以降低出现残疾和经济困难的可能性。

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本文引用的文献

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Health literacy and behaviors influencing blood sugar level control among type 2 diabetes patients in primary care units, Thailand: A cross-sectional study.泰国基层医疗单位2型糖尿病患者的健康素养及影响血糖水平控制的行为:一项横断面研究。
F1000Res. 2022 Mar 18;11:332. doi: 10.12688/f1000research.74225.1. eCollection 2022.
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Perspectives on Aging and Quality of Life.衰老与生活质量的观点
Healthcare (Basel). 2023 Jul 26;11(15):2131. doi: 10.3390/healthcare11152131.
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The impact of health literacy interventions on glycemic control and self-management outcomes among type 2 diabetes mellitus: A systematic review.健康素养干预对 2 型糖尿病患者血糖控制和自我管理结局的影响:系统评价。
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BMC Geriatr. 2023 May 16;23(1):297. doi: 10.1186/s12877-023-04010-0.
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Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress.2型糖尿病中的胰腺β细胞功能障碍:炎症和氧化应激的影响
World J Diabetes. 2023 Mar 15;14(3):130-146. doi: 10.4239/wjd.v14.i3.130.
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