Department of Pharmacy, College of Health Sciences, Debre Markos University, P.O. Box 269, Debre Markos, Ethiopia.
Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Sci Rep. 2024 Oct 5;14(1):23198. doi: 10.1038/s41598-024-72981-0.
Diabetes self-care activities are essential for achieving optimal glycemic control. However, little investigation has been conducted in Ethiopia to evaluate the relationship between the rate glycemic controland self-care activities among patients with type 2 diabetes mellitus (T2DM). Therefore, this study was conducted to assess self -care activities and their association with glycemic control among patients with T2DM in Northwest Ethiopia general hospitals. This multicenter cross-sectional study was conducted in Northwest Ethiopia general hospitals diabetic clinics. Diabetes self-care activities were measured using the Amharic version of the Summary of Diabetes Self-Care Activities (SDSCA-Amharic). Glycated hemoglobin (HbA1c) were used to assess the rate of glycemic control. A linear regression model was used to identify predictors of self-care activities and glycemic control. P-value of < 0.05 at 95% confidence interval (CI) was considerd as statistically significant. Of 413 participants included in the final analysis, two-thirds (66.3%) had poor glycemic control, with a mean HbA1c of 7.94% (SD = 1.75). Blood glucose testing was the most important self-care activity domain for predicting better glycemic control [β=-0.36, 95% CI (-0.48, -0.24); P = 0.0001] followed by diet [β=-0.29, 95% CI (-0.39, -0.083); P = 0.0001], foot-care [β=-0.28, 95% CI (-0.3, -0.061); P = 0.003], and physical activity [β=-0.27, 95% CI (-0.29, -0.056); P = 0.004], respectively. Moreover, unable to read and write [β = 0.72, 95% CI (0.57, 3.8); P = 0.037], overweight [β = 0.32, 95% CI (0.011, 0.62); P = 0.042], obesity [β = 0.67, 95% CI (0.39, 0.94); P = 0.0001], and low level of medication adherence [β = 0.7, 95% CI (0.39, 1.1); P = 0.0001] were significant predictors of poor glycemic control. Previous diabetes education [β=-0.88, 95% CI (-1.2, -0.57); P=0.0001] was a significant predictor of good glycemic control. The prevalence of poor glycemic control and poor self-care activities were high among patients with T2DM. Self-care activities were independent predictors of glycemic control among patients with T2DM. Therefore, management interventions for patients with T2DM should focus on improving self-care activities and other predictor variables.
糖尿病自我护理活动对于实现血糖控制的最佳效果至关重要。然而,在埃塞俄比亚,很少有研究评估 2 型糖尿病(T2DM)患者的血糖控制率和自我护理活动之间的关系。因此,本研究旨在评估西北埃塞俄比亚综合医院 T2DM 患者的自我护理活动及其与血糖控制的关系。这是一项在西北埃塞俄比亚综合医院糖尿病诊所进行的多中心横断面研究。采用阿姆哈拉语版糖尿病自我护理活动综合评估(SDSCA-Amharic)来评估糖尿病自我护理活动。糖化血红蛋白(HbA1c)用于评估血糖控制率。线性回归模型用于确定自我护理活动和血糖控制的预测因素。95%置信区间(CI)的 P 值<0.05 被认为具有统计学意义。在最终分析的 413 名参与者中,三分之二(66.3%)血糖控制不佳,平均 HbA1c 为 7.94%(SD=1.75)。血糖检测是预测更好血糖控制的最重要的自我护理活动领域[β=-0.36,95%CI(-0.48,-0.24);P=0.0001],其次是饮食[β=-0.29,95%CI(-0.39,-0.083);P=0.0001]、足部护理[β=-0.28,95%CI(-0.3,-0.061);P=0.003]和身体活动[β=-0.27,95%CI(-0.29,-0.056);P=0.004]。此外,无法读写[β=0.72,95%CI(0.57,3.8);P=0.037]、超重[β=0.32,95%CI(0.011,0.62);P=0.042]、肥胖[β=0.67,95%CI(0.39,0.94);P=0.0001]和低药物依从性[β=0.7,95%CI(0.39,1.1);P=0.0001]是血糖控制不佳的显著预测因素。之前的糖尿病教育[β=-0.88,95%CI(-1.2,-0.57);P=0.0001]是血糖控制良好的显著预测因素。T2DM 患者血糖控制不佳和自我护理活动较差的情况较为普遍。自我护理活动是 T2DM 患者血糖控制的独立预测因素。因此,T2DM 患者的管理干预措施应侧重于改善自我护理活动和其他预测变量。