Bettelheim F A, Ali S, White O, Chylack L T
Invest Ophthalmol Vis Sci. 1986 Jan;27(1):122-5.
Twenty-nine cataractous human lenses between the ages of 36 and 93 were investigated. The total water content of cortex and nucleus were obtained by vacuum dehydration. The freezable water content was measured by differential scanning calorimetry. The non-freezable water content was obtained by difference. To measure the extent that syneresis contributes to cataract formation, an excess function was designed. The excess function represents the changes that occur, for example, in non-freezable water content due to cataractogenesis. It is calculated as the difference between the non-freezable water content of a normal lens and that of a cataractous lens of the same age. On the average, there is 7% less non-freezable water in the cortex of a cataractous lens than in the cortex of a normal lens. The corresponding number for the nucleus is 9%. This represents 29 and 36% changes, respectively, in the cortex and nucleus due to syneresis during cataractogenesis.
对29个年龄在36至93岁之间的白内障患者晶状体进行了研究。通过真空脱水获得皮质和核的总含水量。用差示扫描量热法测量可冻结水含量。不可冻结水含量通过差值获得。为了测量脱水收缩对白内障形成的影响程度，设计了一个过剩函数。过剩函数表示例如由于白内障形成而在不可冻结水含量中发生的变化。它计算为正常晶状体和同一年龄白内障晶状体的不可冻结水含量之差。平均而言，白内障晶状体皮质中的不可冻结水比正常晶状体皮质中的少7%。核的相应数字是9%。这分别代表白内障形成过程中由于脱水收缩导致皮质和核中29%和36%的变化。
