O'Callaghan W G, Colavita P G, Kay G N, Ellenbogen K A, Gilbert M R, German L D
J Am Coll Cardiol. 1986 Jan;7(1):167-71. doi: 10.1016/s0735-1097(86)80276-5.
Accessory pathway electrograms are rarely recorded in patients with Wolff-Parkinson-White syndrome. In one patient, during electrophysiologic study, simultaneous local ventricular (V) accessory pathway (AP) and atrial (A) deflections were recorded during bipolar catheter endocardial mapping over the pathway. Analysis of changes in electrographic intervals during performance of the ventricular extrastimulus technique allowed characterization of the retrograde conduction properties of the pathway. As coupling intervals were decreased, an initial increase was seen in the AP2A2 interval with subsequent ventriculoatrial block between the accessory pathway and atrium. When coupling intervals were further decreased, the V2AP2 interval lengthened with ultimate block between the ventricle and accessory pathway. These findings support the concept of impedance mismatch as the cause of conduction block in accessory pathways with the distal junction of the accessory pathway being the most vulnerable.
预激综合征患者很少记录到旁路电图。在一名患者的电生理研究中，在经导管心内膜标测该旁路时，同步记录到了局部心室（V）、旁路（AP）和心房（A）的电位变化。通过分析心室额外刺激技术操作过程中电图间期的变化，得以对该旁路的逆向传导特性进行特征描述。随着偶联间期缩短，AP2A2间期最初增加，随后旁路与心房之间出现室房阻滞。当偶联间期进一步缩短时，V2AP2间期延长，最终心室与旁路之间出现阻滞。这些发现支持了阻抗失配是旁路传导阻滞原因的观点，且旁路的远端连接处最为脆弱。
