Sreedharan Sanitha Adithya, Sinha Sujeet Kumar
Department of Audiology, All India Institute of Speech and Hearing, Mysore, Karnataka.
Center for Persons with Tinnitus and Vestibular Disorders, Department of Audiology, All India Institute of Speech and Hearing, Mysore, Karnataka.
Am J Audiol. 2024 Dec 2;33(4):1257-1269. doi: 10.1044/2024_AJA-24-00107. Epub 2024 Oct 16.
The study's objective was to evaluate the functioning of sacculocollic and vestibulomasseteric reflex pathways in individuals with vestibular migraine and migraine.
Seventy-five participants aged 18-50 years were selected for the study. Participants were divided into three groups. Group 1 consisted of 25 healthy individuals, Group 2 consisted of 25 migraine individuals, and Group 3 consisted of 25 individuals with vestibular migraine. Cervical vestibular-evoked myogenic potential (cVEMP) and masseter vestibular-evoked myogenic potential (mVEMP) were recorded using a 500-Hz tone burst stimulus presented at 125 dB peSPL for all participants.
The cVEMP test results showed a delayed p13 and n23 latency for both migraine and vestibular migraine individuals when compared to healthy individuals. Also, the amplitude of the p13-n23 peak was reduced compared to healthy individuals in both migraine and vestibular migraine. Similarly, the mVEMP test results showed a delayed p11 and n21 latency for both migraine and vestibular migraine individuals. No difference was observed in the amplitude of the p11-n21 peak complex between the three groups. Spearman's rho correlation revealed no significant ( > .05) correlation between cervical and masseter VEMP latency and amplitude parameters between healthy, migraine, and vestibular migraine individuals.
The results of the study are suggestive of the pathology of the sacullocollic and vestibulomasseteric reflex pathways in individuals with migraine and vestibular migraine. Individuals with migraine and vestibular migraine should undergo a detailed vestibular evaluation.
本研究的目的是评估前庭性偏头痛和偏头痛患者的球囊-颈反射及前庭-咬肌反射通路的功能。
选取75名年龄在18至50岁之间的参与者进行研究。参与者被分为三组。第一组由25名健康个体组成，第二组由25名偏头痛患者组成，第三组由25名前庭性偏头痛患者组成。对所有参与者使用500赫兹短纯音刺激，以125分贝等效声压级呈现，记录颈前庭诱发肌源性电位（cVEMP）和咬肌前庭诱发肌源性电位（mVEMP）。
与健康个体相比，偏头痛和前庭性偏头痛个体的cVEMP测试结果显示p13和n23潜伏期延迟。此外，偏头痛和前庭性偏头痛个体的p13 - n23峰的振幅与健康个体相比均降低。同样，mVEMP测试结果显示偏头痛和前庭性偏头痛个体的p11和n21潜伏期延迟。三组之间p11 - n21峰复合体的振幅未观察到差异。Spearman等级相关分析显示，健康个体、偏头痛个体和前庭性偏头痛个体的颈和咬肌VEMP潜伏期及振幅参数之间无显著（>0.05）相关性。
研究结果提示偏头痛和前庭性偏头痛患者存在球囊-颈反射及前庭-咬肌反射通路的病理改变。偏头痛和前庭性偏头痛患者应接受详细的前庭评估。
