Carlsen O, Kvinesdal B, Nathan E
J Nucl Med. 1986 Jan;27(1):117-27.
In a retrospective study of 39 normal children submitted to [123I]hippuran gamma camera renography, a quantitative evaluation of the recorded data showed that: (a) the rate constant for renal plasma clearance of [123I]hippuran was -0.166 +/- 0.043 min-1 corresponding to a hippuran plasma clearance of 518 +/- 142 ml/min per 1.73 m2; (b) the fractional renal clearance of [123I]hippuran was 0.51 +/- 0.03 and 0.49 +/- 0.03 for the left and the right kidney, respectively; and (c) the mean values for the mean transit times of [123I]hippuran through the whole kidney, the renal parenchyma, and the renal pelvis, respectively, were 4.2, 1.9, and 2.5 min. Five kidneys (in four patients) showed prolonged renal mean transit times of [123I]hippuran. Follow-up renographies were performed in three of the four children and gave normal results. Patients with renal mean transit times above the present 5% significance limit of 8.2 min should not necessarily be considered having an abnormal renal function.
在一项对39名接受[123I]马尿酸γ相机肾图检查的正常儿童的回顾性研究中，对记录数据的定量评估显示：(a)[123I]马尿酸的肾血浆清除率常数为-0.166±0.043分钟-1，相当于每1.73平方米的马尿酸血浆清除率为518±142毫升/分钟；(b)[123I]马尿酸的肾清除分数，左肾为0.51±0.03，右肾为0.49±0.03；(c)[123I]马尿酸通过整个肾脏、肾实质和肾盂的平均通过时间的平均值分别为4.2分钟、1.9分钟和2.5分钟。五例肾脏（四名患者）显示[123I]马尿酸的肾脏平均通过时间延长。对四名儿童中的三名进行了随访肾图检查，结果正常。肾脏平均通过时间高于目前8.2分钟的5%显著性界限的患者不一定被认为肾功能异常。
