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经皮肾镜取石术治疗近端嵌顿性输尿管结石患者无石率和并发症的预测因素:基于新的评分标准。

Predictive factors of stone-free rate and complications in patients with proximal impacted ureteral stones undergoing percutaneous nephrolithotomy: based on a new scoring standard.

机构信息

Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Institute of Urology, Anhui Medical University, Hefei, China.

出版信息

Urolithiasis. 2024 Oct 16;52(1):149. doi: 10.1007/s00240-024-01647-3.

Abstract

To evaluate the predictive factors affecting the stone-free rate (SFR) and complications of percutaneous nephrolithotomy (PCN) in the treatment of proximal impacted ureteral stones (PIUS) based on a new scoring standard. The data of 90 patients with PIUS were collected in this retrospective study between January 2015 and June 2023. Univariate and multivariate logistic regression analyses were used to determine factors affecting treatment outcome in terms of SFR and complications. The scoring standard for patients with PIUS was developed based on the univariate logistic regression analyses. In the univariate analysis, stone density (P = 0.015), and stone diameter (P = 0.032) significantly were associated with lower SFR. And degree of hydronephrosis (P = 0.014), Preoperative infection (P = 0.002), and history of lithotripsy (P = 0.045) were associated with occurrence of complications. Multivariate analysis indicated that stone density (P = 0.020), and stone diameter (P < 0.001) were associated with lower SFR; independent risk factors for development of complications were history of lithotripsy (P = 0.024), and preoperative infection (P < 0.001). Additionally, score ≥ 3 was the independent risk factor for both SFR (P < 0.001) and complication rate (P < 0.001). Subgroup analysis shown that there were statistically significant differences between the two groups in terms of stone-free rate (P = 0.032) and complications (P = 0.015). According to the findings of this study, the stone score ≥ 3 was determined as a critical predictive factor of SFR and complications in PIUS patients undergoing PCN based on a new scoring standard. Additionally, PCN has high initial SFR and low complications when dealing with score < 3 PIUS.

摘要

基于新的评分标准,评估影响经皮肾镜碎石术(PCNL)治疗近端嵌顿输尿管结石(PIUS)患者无石率(SFR)和并发症的预测因素。本回顾性研究收集了 2015 年 1 月至 2023 年 6 月间 90 例 PIUS 患者的数据。采用单因素和多因素逻辑回归分析确定影响 SFR 和并发症的治疗结果的因素。基于单因素逻辑回归分析,为 PIUS 患者制定评分标准。在单因素分析中,结石密度(P=0.015)和结石直径(P=0.032)与较低的 SFR 显著相关。而肾积水程度(P=0.014)、术前感染(P=0.002)和碎石史(P=0.045)与并发症的发生相关。多因素分析表明,结石密度(P=0.020)和结石直径(P<0.001)与较低的 SFR 相关;发生并发症的独立危险因素是碎石史(P=0.024)和术前感染(P<0.001)。此外,评分≥3 是 SFR(P<0.001)和并发症发生率(P<0.001)的独立危险因素。亚组分析表明,两组在无石率(P=0.032)和并发症发生率(P=0.015)方面存在统计学差异。根据本研究的结果,基于新的评分标准,结石评分≥3 被确定为 PCNL 治疗 PIUS 患者 SFR 和并发症的关键预测因素。此外,当处理评分<3 的 PIUS 时,PCN 具有较高的初始 SFR 和较低的并发症发生率。

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