Vascular Health Unit, Research Institute of McGill University Health Centre (RI-MUHC), Montreal, QC, Canada.
Division of Experimental Medicine, Department of Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada.
J Hum Hypertens. 2024 Nov;38(11):745-749. doi: 10.1038/s41371-024-00967-6. Epub 2024 Oct 16.
Preeclampsia is a leading complication of pregnancy that lacks accurate tools for its early prediction. Improved risk stratification tools early in pregnancy would enable more efficient allocation of limited healthcare resources while ensuring that pregnant women destined to develop preeclampsia receive appropriate care. This brief perspective highlights the current state of first-trimester preeclampsia prediction. We focus on arterial stiffness, an important hemodynamic indicator of vascular health that has shown promising results for improved early prediction of preeclampsia by our and independent research groups. Further, we outline the promise, applicability, and feasibility of integrating arterial stiffness assessments into clinical practice.
子痫前期是妊娠的主要并发症之一,但目前缺乏其早期预测的准确工具。如果能在妊娠早期获得更好的风险分层工具,就可以更有效地分配有限的医疗保健资源,同时确保那些注定会发展为子痫前期的孕妇得到适当的护理。本简要观点重点介绍了子痫前期的早期预测的当前现状。我们重点介绍了动脉僵硬度,这是血管健康的一个重要血流动力学指标,我们和独立研究小组的研究都表明,它在改善子痫前期的早期预测方面具有广阔的前景。此外,我们还概述了将动脉僵硬度评估纳入临床实践的前景、适用性和可行性。