Seltzer S, McCabe B F
Laryngoscope. 1986 Jan;96(1):37-49. doi: 10.1288/00005537-198601000-00007.
Ninety-one patients with demonstrable perilymph fistulas presented with an amazing array of signs and symptoms ranging from unilateral tinnitus and aural fullness to sudden-and-profound hearing loss, roaring tinnitus, and whirling vertigo. Between 1977 and 1984, 214 exploratory tympanotomies for suspected perilymph fistula (PLF) were performed on 177 patients. One hundred six primary (initial) fistulas were found in 95 ears and 26 recurrent fistulas were identified. Eighty-two percent of the 91 patients with PLF had auditory symptoms, 8% with auditory symptoms as the sole complaint. Eighty-one percent of the patients had vestibular symptoms, 12% with vestibular symptoms alone. The type of hearing loss and the nature of the vestibular symptoms were widely variable. Of the 58 patients with preoperative auditory symptoms, 49% had improved hearing (23% improved to serviceable range), after closure of PLFs. Ninety-five percent of the patients who presented with vestibular symptoms had elimination of or decrease in their dizziness to the extent that it no longer interfered with their daily activities. The highest incidence of recurrent fistula was associated with grafts using fatty tissue. Patients with Mondini deformity were at particularly high risk for fistula recurrence.
91例确诊为外淋巴瘘的患者表现出一系列惊人的体征和症状,从单侧耳鸣、耳闷到突然性重度听力损失、轰鸣性耳鸣和旋转性眩晕。1977年至1984年间,对177例患者进行了214次针对疑似外淋巴瘘(PLF)的探查性鼓室切开术。在95只耳朵中发现了106个原发性(初始)瘘管,并识别出26个复发性瘘管。91例PLF患者中,82%有听觉症状,其中8%仅以听觉症状为主诉。81%的患者有前庭症状,其中12%仅以前庭症状为主诉。听力损失的类型和前庭症状的性质差异很大。58例术前有听觉症状的患者中,49%在PLF闭合后听力有所改善(23%改善到可使用范围)。95%有前庭症状的患者头晕症状消除或减轻,不再影响其日常活动。复发性瘘管的最高发生率与使用脂肪组织的移植物有关。Mondini畸形患者瘘管复发的风险特别高。