Institute of Advanced Biotechnology and School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Max Planck Institute for Biology of Ageing, Cologne, Germany.
Aging (Albany NY). 2024 Oct 16;16(20):12955-12976. doi: 10.18632/aging.206135.
The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan.
近年来，衰老研究和药物发现取得了前所未有的进展，将基础研究和临床应用结合起来，推进了提高人类人口健康长寿的目标。我们在 2023 年衰老研究和药物发现会议上总结了健康寿命生物技术的最新进展，特别强调了人工智能 (AI)、生物标志物和时钟、衰老科学，以及健康长寿的临床试验和干预措施。此外，我们还概述了专注于靶向衰老作为与年龄相关疾病根源的学术研究和生物技术行业，以对抗多种疾病并延长健康寿命。我们提出，生成式人工智能、前沿生物技术和长寿医学的融合对于延长人类有生产力和健康的寿命至关重要。
