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多层流调节支架在动脉动脉瘤治疗中的作用。

Role of multilayer flow modulator stents in the treatment of arterial aneurysms.

机构信息

INVAMED Medical Innovation Institute, Mutlukent Mah. 1961 Cd. No. 27, Cankaya, Ankara 06810, Turkey.

Antalya Provincial Health Directorate, Antalya, Turkey.

出版信息

Ther Adv Cardiovasc Dis. 2024 Jan-Dec;18:17539447241283736. doi: 10.1177/17539447241283736.

Abstract

Arterial aneurysms remain a significant public health problem because they often result in death when ruptured; therefore, they require immediate medical treatment. Endovascular aneurysm repair (EVAR) has recently become the primary treatment option, owing to the fewer side effects compared to those with open surgery. However, stents used for conventional EVAR often cause side-branch occlusion, which alters the perfusion of vital organs. Recently, multilayer flow modulator (MFM) stents have been used as a new treatment for arterial aneurysms. These stents appear to be feasible owing to their unique design consisting of an uncoated three-dimensionally braided multilayered structure. MFM stents generally remodulate laminar flow and reduce the flow velocity in the aneurysmal sac, leading to thrombosis, which causes the aneurysm to shrink over time. Thus, they reduce the risk of mortality. Moreover, they reduce morbidity by preserving the side-branch blood flow. They can be easily applied to complex aneurysms and are ready to use without customization, which shortens the waiting time for interventions. This study aimed to evaluate the role of MFM stents in the treatment of arterial aneurysms based on available data.

摘要

动脉动脉瘤仍然是一个重大的公共卫生问题,因为它们在破裂时常常导致死亡;因此,需要立即进行医疗治疗。血管内动脉瘤修复术 (EVAR) 最近已成为主要的治疗选择,因为与开放手术相比,它的副作用更少。然而,用于传统 EVAR 的支架常常导致侧支闭塞,从而改变重要器官的灌注。最近,多层流量调制器 (MFM) 支架已被用作治疗动脉动脉瘤的新方法。这些支架由于其独特的设计,由未涂层的三维编织多层结构组成,因此似乎是可行的。MFM 支架通常使层流重新调节并降低动脉瘤囊中血流速度,导致血栓形成,从而使动脉瘤随时间缩小。因此,它们降低了死亡率。此外,它们通过保留侧支血流来降低发病率。它们可以很容易地应用于复杂的动脉瘤,并且无需定制即可随时使用,从而缩短了介入治疗的等待时间。本研究旨在根据现有数据评估 MFM 支架在治疗动脉动脉瘤中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f89c/11489923/68c95f3261fe/10.1177_17539447241283736-fig1.jpg

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