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揭开肥胖的神秘面纱:理解、预防、治疗及相关污名

Demystifying Obesity: Understanding, Prevention, Treatment, and Stigmas.

作者信息

Minari Tatiana Palotta, Manzano Carolina Freitas, Yugar Louise Buonalumi Tácito, Sedenho-Prado Luis Gustavo, de Azevedo Rubio Tatiane, Tácito Lúcia Helena Bonalumi, Pires Antônio Carlos, Vilela-Martin José Fernando, Cosenso-Martin Luciana Neves, Ludovico Nelson Dinamarco, Fattori André, Yugar-Toledo Juan Carlos, Moreno Heitor, Pisani Luciana Pellegrini

机构信息

Department of Hypertension, State Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.

School of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.

出版信息

Nutr Rev. 2025 Jul 1;83(7):e1983-e2008. doi: 10.1093/nutrit/nuae144.

Abstract

Obesity is a complex chronic disease that affects millions of people worldwide. There is still significant stigma associated with it, which can lead to discrimination and create additional barriers for people who are already in treatment. On the other hand, it is noted that it can have serious implications for health and predisposition to noncommunicable chronic diseases. In this sense, the objective of this study was to carry out a narrative review involving all current elements for understanding, prevention, treatment, and debate of stigmas related to obesity. A search was conducted in 2024 for original articles, randomized or nonrandomized clinical trials, systematic reviews, meta-analyses, and guidelines in the following databases: Pubmed, Scielo, Web of Science, CrossRef, and Google Scholar. The publication period was from 2014 to 2024. Obesity is influenced by a complex combination of genetic, environmental, and psychological factors. It is encouraging to see that various emerging points have been identified across different fields such as histology, physiology, genetics, weight loss, and public policy. These obesity areas certainly warrant attention and future studies. Researchers can delve into these topics to deepen their understanding and potentially uncover novel insights. The management should be multifactorial and individualized for each patient. Public policies also play a crucial role in combating obesity, including health promotion, prevention of excessive weight gain, early diagnosis, and proper care of patients. It is crucial that society begins to see the disease as an extremely complex element and not as a moral failure or lack of willpower. This requires a change in the way people talk about obesity, as well as practices that support people instead of stigmatizing them. Obesity does not have a specific address, color, or race. It belongs to everyone and should be regarded as a global public health problem.

摘要

肥胖是一种复杂的慢性疾病,影响着全球数百万人。与之相关的耻辱感仍然很严重,这可能导致歧视,并给正在接受治疗的人带来额外的障碍。另一方面,值得注意的是,肥胖会对健康以及患非传染性慢性病的易感性产生严重影响。从这个意义上说,本研究的目的是进行一项叙述性综述,涵盖当前所有与肥胖相关的耻辱感的理解、预防、治疗及相关讨论的要素。2024年,我们在以下数据库中检索了原创文章、随机或非随机临床试验、系统评价、荟萃分析和指南:PubMed、Scielo、科学网、CrossRef和谷歌学术。发表时间为2014年至2024年。肥胖受到遗传、环境和心理因素的复杂综合影响。令人鼓舞的是,在组织学、生理学、遗传学、减肥和公共政策等不同领域已经发现了各种新出现的要点。这些肥胖领域无疑值得关注和未来的研究。研究人员可以深入研究这些主题,以加深理解并可能发现新的见解。管理应该是多因素的,并且针对每个患者进行个性化。公共政策在对抗肥胖方面也起着至关重要的作用,包括健康促进、预防体重过度增加、早期诊断以及对患者的妥善护理。至关重要的是,社会应开始将这种疾病视为一个极其复杂的因素,而不是道德失败或缺乏意志力。这需要人们谈论肥胖的方式发生改变,以及采取支持而非污名化人们的做法。肥胖没有特定的住址、肤色或种族。它属于每个人,应被视为一个全球公共卫生问题。

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