Llerena-Velastegui Jordan, Lopez-Usina Almendra, Mantilla-Cisneros Camila
Medical School, Pontifical Catholic University of Ecuador, Quito, Ecuador.
Research Center, Center for Health Research in Latin America (CISeAL), Quito, Ecuador. Email:
Cardiol Res. 2024 Oct;15(5):340-349. doi: 10.14740/cr1665. Epub 2024 Sep 16.
Chronic Chagas cardiomyopathy (CCC) poses significant health challenges not only in Latin America but also in non-endemic regions due to global migration. The complexity and severity of CCC call for an updated and thorough review to inform clinical practices and direct future research efforts. This review seeks to consolidate current knowledge on CCC, emphasizing diagnostic, therapeutic, and prognostic facets to facilitate better management and understanding of the disease. An exhaustive examination was conducted, analyzing peer-reviewed articles published between January 2020 and April 2024, sourced from prominent medical databases such as PubMed and Scopus. The review delineates crucial aspects of CCC pathophysiology, evaluates patient outcomes, identifies diagnostic challenges, and assesses treatment efficacy. Our findings prompt the need for revised clinical guidelines and stress the importance of continued research to enhance therapeutic strategies and disease comprehension. It is imperative that future studies address these identified gaps to advance patient care and treatment options for CCC.
慢性恰加斯心肌病（CCC）不仅在拉丁美洲，而且由于全球移民，在非流行地区也带来了重大的健康挑战。CCC的复杂性和严重性要求进行更新和全面的综述，以为临床实践提供信息并指导未来的研究工作。本综述旨在整合关于CCC的现有知识，强调诊断、治疗和预后方面，以促进对该疾病的更好管理和理解。我们进行了详尽的研究，分析了2020年1月至2024年4月期间发表的同行评审文章，这些文章来自PubMed和Scopus等著名医学数据库。该综述阐述了CCC病理生理学的关键方面，评估了患者预后，识别了诊断挑战，并评估了治疗效果。我们的研究结果表明需要修订临床指南，并强调持续研究对于加强治疗策略和疾病理解的重要性。未来的研究必须解决这些已发现的差距，以推进CCC患者的护理和治疗选择。
