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一名成年女性使用左氧氟沙星后发生的IgA血管炎:病例报告

IgA Vasculitis Associated With Levofloxacin Use in an Adult Female: A Case Report.

作者信息

Gómez Contreras Karen A, Alonzo Canul María E, Mena Rodríguez Ana L, Castillo Baas Melissa G, Vargas Gutiérrez David A

机构信息

Internal Medicine, Clínica Hospital Mérida, Mérida, MEX.

Dermatology, Clínica Hospital Mérida, Mérida, MEX.

出版信息

Cureus. 2024 Oct 15;16(10):e71567. doi: 10.7759/cureus.71567. eCollection 2024 Oct.

Abstract

Immunoglobulin A (IgA) vasculitis, once known as Henoch-Schönlein purpura in recognition of the physicians who first identified it, is an acute form of vasculitis, associated with a deposition of immune complexes, self-limited that affects small-caliber vessels. It usually occurs in children and rarely in adults. This disease can be induced by multiple factors such as exposure to certain infectious antigens such as viruses or bacteria, drugs, and toxins, and even genetic predisposition has been described. Although the use of some antibiotics is known as a risk factor for the development of IgA vasculitis, it may not be considered when approaching and treating an adult with a related clinical condition, since its frequency is rare. We present the case of a 26-year-old woman with a history of an upper respiratory tract infection who required treatment with levofloxacin and subsequently developed palpable purpura.

摘要

免疫球蛋白A(IgA)血管炎,曾因纪念首次发现它的医生而被称为亨诺-许兰紫癜,是一种急性血管炎,与免疫复合物沉积有关,呈自限性,累及小口径血管。它通常发生于儿童,在成人中罕见。这种疾病可由多种因素诱发,如接触某些感染性抗原(如病毒或细菌)、药物和毒素,甚至有遗传易感性的描述。虽然已知使用某些抗生素是IgA血管炎发病的一个危险因素,但在诊治患有相关临床病症的成人时可能不会考虑到这一点,因为其发生率很低。我们报告一例26岁有上呼吸道感染病史的女性病例,该患者因使用左氧氟沙星治疗,随后出现可触及的紫癜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf49/11485585/0e58d64c9a0f/cureus-0016-00000071567-i01.jpg

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