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强调萘普生预防的重要性可能会降低髋关节镜检查后异位骨化的发生率。

Emphasizing the Importance of Naproxen Prophylaxis May Decrease the Rate of Heterotopic Ossification After Hip Arthroscopy.

作者信息

Khalil Ameen Z, McNamara Natalya E, Featherall Joseph, Metz Allan K, Lewis Daniel C, Aoki Stephen K

机构信息

Department of Orthopaedics, University of Utah, Salt Lake City, Utah, U.S.A.

出版信息

Arthrosc Sports Med Rehabil. 2024 Apr 9;6(4):100941. doi: 10.1016/j.asmr.2024.100941. eCollection 2024 Aug.

Abstract

PURPOSE

To investigate the incidence of heterotopic ossification (HO) in patients prescribed prophylactic nonsteroidal anti-inflammatory drugs (NSAIDs), both before and after the introduction of a standardized education protocol.

METHODS

A retrospective review was conducted using a database of hip arthroscopy patients treated by a single surgeon at an academic hospital from 2015 to 2023. The inclusion criteria were (1) primary hip arthroscopy for the treatment of femoroacetabular impingement, (2) completion of a 2-week course of prophylactic postoperative NSAIDs (500 mg of naproxen twice daily), and (3) availability of follow-up radiographs at the 6-month postoperative visit. The control cohort was merely prescribed the postoperative prophylactic NSAIDs, whereas the intervention cohort also received dedicated in-person education, emphasizing the importance of NSAID adherence. The presence of HO was determined through review of follow-up radiographs. Standard descriptive statistics were used to describe the findings.

RESULTS

Both the control and intervention groups consisted of 200 continuous hip arthroscopy patients, with the control group treated from 2015 to 2017 and the intervention group treated from 2020 to 2023. Within the control group, 10 cases of HO (5%) were detected. Within the intervention group, 2 cases of HO (1%) were found. The Pearson χ test with Yates continuity correction produced a value of 4.21, with a value of .04.

CONCLUSIONS

In this study, we found a significantly lower incidence rate of HO in patients who received standardized education on the importance of NSAID compliance versus those who did not. This finding suggests that patient education may play a contributory role in reducing the incidence of HO after hip arthroscopy.

LEVEL OF EVIDENCE

Level III, comparative cohort study.

摘要

目的

研究在引入标准化教育方案前后,接受预防性非甾体抗炎药(NSAIDs)治疗的患者中异位骨化(HO)的发生率。

方法

对2015年至2023年在一家学术医院由同一位外科医生治疗的髋关节镜检查患者数据库进行回顾性研究。纳入标准为:(1)因股骨髋臼撞击症接受初次髋关节镜检查;(2)完成术后为期2周的预防性NSAIDs疗程(每日两次,每次500毫克萘普生);(3)术后6个月随访时有X光片。对照组仅接受术后预防性NSAIDs治疗,而干预组还接受了专门的现场教育,强调坚持服用NSAIDs的重要性。通过复查随访X光片确定是否存在HO。使用标准描述性统计来描述研究结果。

结果

对照组和干预组均由200例连续接受髋关节镜检查的患者组成,对照组于2015年至2017年接受治疗,干预组于2020年至2023年接受治疗。对照组中检测到10例HO(5%)。干预组中发现2例HO(1%)。经Yates连续性校正的Pearson χ检验值为4.21,P值为0.04。

结论

在本研究中,我们发现,与未接受NSAIDs依从性重要性标准化教育的患者相比,接受该教育的患者HO发生率显著更低。这一发现表明,患者教育可能在降低髋关节镜检查后HO的发生率方面发挥作用。

证据水平

III级,比较队列研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8f4/11480793/c865061ee461/gr1.jpg

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