Marshall Grace, Byrne Matthew, Wirth Korry, Liao Xiaoyan, Linehan David C, Wilson Nicole A
University of Rochester School of Medicine and Dentistry, Rochester, New York.
Department of Surgery, University of Rochester Medical Center, Rochester, New York.
European J Pediatr Surg Rep. 2024 Oct 17;12(1):e58-e62. doi: 10.1055/s-0044-1791812. eCollection 2024 Jan.
Solid pseudopapillary neoplasm (SPN) is a rare low-grade malignant tumor of the pancreas that occurs predominantly in young females. This tumor is occasionally multicentric, posing a unique surgical conundrum for resection. We present a case of a 10-year-old female with a history of multicystic dysplastic left kidney and persistent urogenital sinus who was diagnosed with biopsy-proven multicentric SPN of the pancreatic head and tail and underwent middle-preserving pancreatectomy. The patient tolerated the surgery very well. Our case is one of the few reported cases of multicentric SPN in a pediatric patient, and the only case treated with middle-preserving pancreatectomy, which is a novel surgical option for protecting pediatric patients from total endocrine and exocrine pancreatic insufficiency. With the increase in the incidence of SPN, there is an increasing need for pancreas-preserving surgical options, particularly in pediatric patients.
实性假乳头状肿瘤（SPN）是一种罕见的胰腺低度恶性肿瘤，主要发生于年轻女性。该肿瘤偶尔为多中心性，给手术切除带来了独特的难题。我们报告一例10岁女性病例，其有左侧多囊性发育不良肾和持续性泌尿生殖窦病史，经活检证实为胰头和胰尾多中心性SPN，并接受了保留中段的胰腺切除术。患者对手术耐受性良好。我们的病例是儿科患者中少数报道的多中心性SPN病例之一，也是唯一接受保留中段胰腺切除术治疗的病例，这是一种保护儿科患者避免出现完全性胰腺内分泌和外分泌功能不全的新型手术选择。随着SPN发病率的增加，对保留胰腺的手术选择的需求日益增加，尤其是在儿科患者中。
