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增强健康和治疗潜力：大豆生物活性化合物的药用和制药特性创新

Enhancing health and therapeutic potential: innovations in the medicinal and pharmaceutical properties of soy bioactive compounds.

作者信息

Rahman Ubaidur, Younas Zohaib, Ahmad Ilyas, Yousaf Tayyaba, Latif Rafia, Rubab Ume, Hassan Hira, Shafi Unsa, Mashwani Zia-Ur-Rehman

机构信息

Department of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, Pakistan.

出版信息

Front Pharmacol. 2024 Oct 3;15:1397872. doi: 10.3389/fphar.2024.1397872. eCollection 2024.

DOI:10.3389/fphar.2024.1397872
PMID:39421675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11483366/
Abstract

An extensive examination of the medical uses of soybean bioactive components is provided by this thorough review. It explores the possible health advantages of isoflavones with phytoestrogenic qualities, like genistein, which may lower the risk of cancer. The review highlights the different roles and possible anticancer activities of phenolic compounds, phytic acid, protease inhibitors, lignans, and saponins, among other bioactive components. It also addresses the benefits of dietary fiber and oligosaccharides derived from soybeans for intestinal health, as well as the impact of soy protein on diabetes, obesity, cancer, and cardiovascular health. Conjugated linoleic acid (CLA) has anticancer and cholesterol-lowering properties; its involvement in promoting metabolic processes is also examined. Pinitol is highlighted in the study as a blood sugar regulator with promise for controlling insulin signaling. In this review, we aim to affirm soybeans' potential as a high-functional, well-being food by examining their recently discovered therapeutic and pharmacological capabilities, rather than to improve upon the previous studies on the reported nutritional advantages of soybeans.

摘要

这篇全面的综述对大豆生物活性成分的医学用途进行了广泛研究。它探讨了具有植物雌激素特性的异黄酮（如金雀异黄素）可能带来的健康益处，金雀异黄素可能降低患癌风险。该综述强调了酚类化合物、植酸、蛋白酶抑制剂、木脂素和皂苷等生物活性成分的不同作用及可能的抗癌活性。它还讨论了大豆膳食纤维和低聚糖对肠道健康的益处，以及大豆蛋白对糖尿病、肥胖症、癌症和心血管健康的影响。共轭亚油酸（CLA）具有抗癌和降胆固醇特性；其在促进代谢过程中的作用也得到了研究。松醇在该研究中被重点提及，它作为一种血糖调节剂有望控制胰岛素信号传导。在这篇综述中，我们旨在通过研究大豆最近发现的治疗和药理能力，来肯定大豆作为一种高功能性健康食品的潜力，而非改进之前关于大豆所报道的营养优势的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8707/11483366/80f908a7a89b/fphar-15-1397872-g010.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8707/11483366/aaef9ae7e97d/fphar-15-1397872-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8707/11483366/80f908a7a89b/fphar-15-1397872-g010.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8707/11483366/80f908a7a89b/fphar-15-1397872-g010.jpg

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