Choban P S, Schwab C W, Max M H
Am Surg. 1986 Jan;52(1):44-6.
Preexisting coagulopathy or hepatic dysfunction is a potential problem in the alcoholic with penetrating abdominal trauma. This study reviews 36 patients with penetrating abdominal trauma to determine evidence of acute and/or chronic alcohol abuse, evidence of hepatic dysfunction, preexisting coagulopathy, pattern of blood use, and severity of injury. Sixty-four per cent of patients had detectable blood alcohol concentrations (BAC) on admission and 50% were legally intoxicated. Alcohol consumption histories were available for 24 patients, and 15 (63%) were chronic alcohol abusers. There was little evidence of hepatic dysfunction and minimal coagulopathy. There was a significant difference in the number of chronic alcohol abusers who received blood and in the amount used by any individual. There is nothing in this study to suggest this increased blood use would be lessened by including fresh frozen plasma, Vitamin K, or platelet packs in the initial resuscitation of the alcoholic patient with penetrating abdominal trauma.
对于腹部穿透伤的酗酒者而言,既往存在的凝血功能障碍或肝功能不全是一个潜在问题。本研究回顾了36例腹部穿透伤患者,以确定急性和/或慢性酒精滥用的证据、肝功能不全的证据、既往存在的凝血功能障碍、用血模式以及损伤的严重程度。64%的患者入院时血液酒精浓度(BAC)可检测到,50%处于法定醉酒状态。有24例患者有饮酒史,其中15例(63%)为慢性酒精滥用者。几乎没有肝功能不全和凝血功能障碍的证据。接受输血的慢性酒精滥用者数量以及任何个体的用血量存在显著差异。本研究没有任何内容表明,在对腹部穿透伤的酗酒患者进行初始复苏时,加入新鲜冰冻血浆、维生素K或血小板包会减少这种增加的用血情况。