Groden L R, Brinser J H
Arch Ophthalmol. 1986 Jan;104(1):84-6. doi: 10.1001/archopht.1986.01050130094028.
Outpatient and inpatient management of culture-proved microbial corneal ulcers was evaluated. Twenty-six consecutive patients were reviewed. Twenty had been managed as outpatients, six as inpatients. All ulcers were treated with intensive topical antimicrobial therapy, and all steadily healed, as evidenced by epithelialization and resolution of infiltrate. None progressed to extreme stromal thinning, descemetocele, or perforation. Inpatients and outpatients did not differ in terms of healing time, although this can vary considerably for the same causative organism. Complete epithelialization took two to 56 days. Pseudomonas ulcers healed in seven to 42 days (mean, 22 days), which is similar to previously published reports of inpatient therapy. This study suggests that with careful patient selection and follow-up, infectious corneal ulcers can be successfully managed on an outpatient basis.
对经培养证实的微生物性角膜溃疡的门诊和住院治疗情况进行了评估。回顾了连续的26例患者。其中20例接受门诊治疗，6例接受住院治疗。所有溃疡均采用强化局部抗菌治疗，所有溃疡均稳步愈合，表现为上皮化和浸润消退。无一例进展为极度基质变薄、后弹力层膨出或穿孔。住院患者和门诊患者在愈合时间方面没有差异，尽管对于相同的病原体，愈合时间可能有很大差异。完全上皮化需要2至56天。铜绿假单胞菌溃疡在7至42天内愈合（平均22天），这与先前发表的住院治疗报告相似。本研究表明，通过仔细的患者选择和随访，感染性角膜溃疡可以在门诊成功治疗。
