Fischler M, Seigneur F, Bourreli B, Melchior J C, Lavaud C, Vourc'h G
Br J Anaesth. 1986 Jan;58(1):92-8. doi: 10.1093/bja/58.1.92.
Changes in minute ventilation, tracheal airway pressure and lung volume have been measured using a jet ventilator (VS 600) during different rates of ventilation, I:E ratios and driving pressures. A lung model with a slightly increased compliance and an increased airway resistance was used. Five rates of ventilation (from 60 to 230 b.p.m.), three I:E ratios (0.25, 0.43, 0.67) and three driving pressures (200, 300 and 400 kPa) were studied. The increases in the rate of ventilation did not modify minute ventilation significantly, decreased peak airway pressure only slightly and increased end-expiratory pressure and lung volume. The increases in I:E ratio produced increases in minute ventilation, peak airway pressure, end-expiratory pressure and lung volume. The increases in driving pressure induced changes similar to those produced by the alterations in I:E ratio.
在不同的通气频率、吸呼比和驱动压力下，使用喷射呼吸机（VS 600）测量了每分通气量、气管气道压力和肺容积的变化。使用了一个顺应性略有增加且气道阻力增加的肺模型。研究了五种通气频率（从60到230次/分钟）、三种吸呼比（0.25、0.43、0.67）和三种驱动压力（200、300和400 kPa）。通气频率的增加并未显著改变每分通气量，仅略微降低了气道峰值压力，并增加了呼气末压力和肺容积。吸呼比的增加导致每分通气量、气道峰值压力、呼气末压力和肺容积增加。驱动压力的增加引起的变化与吸呼比改变所产生的变化相似。
