Popova N K, Koriakina L A
Biull Eksp Biol Med. 1986 Jan;101(1):11-3.
The role of genetic and seasonal factors in stress-induced changes of pain sensitivity, evaluated by latency in hot plate test was studied. Significant interstrain differences in restriction effect on pain sensitivity was established. Analgesia, hyperalgesia or lack of influence on pain sensitivity in mice of different strains was observed in response to emotional stress. Interstrain differences in seasonal variance of stress-induced changes in pain sensitivity were shown. It is suggested that changes in pain sensitivity of mice after restriction are season-dependent and controlled by hereditary mechanisms.
通过热板试验潜伏期评估了遗传和季节因素在应激诱导的疼痛敏感性变化中的作用。确定了不同品系小鼠在疼痛敏感性限制作用方面存在显著差异。观察到不同品系小鼠在受到情绪应激时出现镇痛、痛觉过敏或对疼痛敏感性无影响的情况。结果显示不同品系小鼠在应激诱导的疼痛敏感性变化的季节差异方面也存在不同。研究表明，限制后小鼠疼痛敏感性的变化具有季节依赖性，并受遗传机制控制。
