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螺旋静脉包裹皮瓣治疗疼痛性神经瘤的手术效果:病例系列分析。

Surgical Outcomes of Spiral Vein Wrapping Flaps for Painful Neuromas: A Case Series Analysis.

机构信息

Department of Orthopedics and Traumatology, RSUP Dr. Sardjito Hospital, Yogyakarta, Indonesia.

Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Sleman, Yogyakarta, Indonesia.

出版信息

Am J Case Rep. 2024 Oct 21;25:e945014. doi: 10.12659/AJCR.945014.

DOI:10.12659/AJCR.945014
PMID:39428641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11502520/
Abstract

BACKGROUND Neuropathic pain symptoms caused by neuromas impose physical burdens and affect patients mentally and socioeconomically. Surgical intervention offers more promising outcomes than do conservative approaches. An accessible and cost-effective surgical treatments is neuroma excision, coupled with nerve wrapping flaps. However, few reports have detailed the outcomes of this approach. In this study, we report 4 patients who underwent neuroma excision and nerve wrapping with vein autographs. CASE REPORT We present 4 patients who experienced persistent neuropathic pain and did not respond to conservative treatment for more than 6 months. Three patients had upper limb neuromas in continuity and 1 patient had a stump femoral neuroma. Surgical intervention involved neuroma excision, nerve grafting, and the application of nerve wrapping flaps at the site of anastomosis. Evaluation of our patients included neuroma pain scores and the Weber 2-point discrimination test. Follow-up assessments demonstrated significant clinical improvement, with all patients showing up to 60% reduction in pain and an average improvement of 5 mm in 2-point discrimination. No recurrence or need for further surgery was observed. CONCLUSIONS Surgical intervention was superior to conservative treatment in patients with painful neuromas. Nerve wrapping flaps, one of the surgical procedures for neuroma management, represents an effective surgical option for neuromas in continuity and stump neuromas. This is related to the more physiological nerve regeneration process when nerve ends are closed. The use of autograft veins as one of the materials for closing nerve ends is advantageous owing to its affordability and versatility in accommodating nerves of varying sizes.

摘要

背景

神经瘤引起的神经性疼痛症状给患者带来身体负担,并在精神和社会经济方面造成影响。手术干预比保守方法提供更有前景的结果。一种可行且具有成本效益的手术治疗方法是神经瘤切除,结合神经包裹皮瓣。然而,很少有报道详细描述这种方法的结果。在本研究中,我们报告了 4 例接受神经瘤切除和静脉自体移植神经包裹的患者。

病例报告

我们介绍了 4 例经历持续性神经性疼痛且对超过 6 个月的保守治疗无反应的患者。3 例患者上肢神经瘤连续存在,1 例患者股骨残端神经瘤。手术干预包括神经瘤切除、神经移植和吻合部位神经包裹皮瓣的应用。我们的患者评估包括神经瘤疼痛评分和 Weber 2 分辨别测试。随访评估显示出显著的临床改善,所有患者的疼痛减轻了 60%,2 分辨别测试的平均改善了 5 毫米。未观察到复发或需要进一步手术。

结论

手术干预优于疼痛性神经瘤患者的保守治疗。神经包裹皮瓣是神经瘤管理的手术程序之一,是连续性神经瘤和残端神经瘤的有效手术选择。这与神经末端封闭时更生理性的神经再生过程有关。使用自体静脉作为封闭神经末端的材料之一具有优势,因为其价格合理且通用性强,可适应不同大小的神经。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f679/11502520/c8848af6a081/amjcaserep-25-e945014-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f679/11502520/3e5ee2567474/amjcaserep-25-e945014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f679/11502520/c8848af6a081/amjcaserep-25-e945014-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f679/11502520/3e5ee2567474/amjcaserep-25-e945014-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f679/11502520/c8848af6a081/amjcaserep-25-e945014-g002.jpg

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本文引用的文献

1
Surgical Algorithm for Neuroma Management: A Changing Treatment Paradigm.神经瘤治疗的手术算法:不断变化的治疗模式
Plast Reconstr Surg Glob Open. 2018 Oct 16;6(10):e1952. doi: 10.1097/GOX.0000000000001952. eCollection 2018 Oct.
2
Surgical Management of Neuromas of the Hand and Wrist.手部和腕部神经瘤的手术治疗。
J Am Acad Orthop Surg. 2019 May 15;27(10):356-363. doi: 10.5435/JAAOS-D-17-00398.
3
Surgical interventions for the treatment of painful neuroma: a comparative meta-analysis.手术干预治疗疼痛性神经瘤:一项比较性荟萃分析。
Pain. 2018 Feb;159(2):214-223. doi: 10.1097/j.pain.0000000000001101.
4
Vein wrapping technique for nerve reconstruction in patients with thyroid cancer invading the recurrent laryngeal nerve.甲状腺癌侵犯喉返神经患者神经重建的静脉包裹技术
Arch Plast Surg. 2012 Jan;39(1):71-5. doi: 10.5999/aps.2012.39.1.71. Epub 2012 Jan 15.
5
Nerve wrapping.神经包裹
Foot Ankle Clin. 2011 Jun;16(2):327-37. doi: 10.1016/j.fcl.2011.01.001.