Parducz A
Brain Res. 1986 Jan 8;362(2):375-8. doi: 10.1016/0006-8993(86)90467-1.
The function-dependent changes in synaptic vesicle number and horseradish peroxidase (HRP) labeling were studied in the synapses of cat superior cervical ganglia. It was found that only a low percentage of vesicles contained the extracellular marker. Supra-maximal stimulation (15 min) and subsequent rest (5 min) did not result in significant changes in vesicle number and the percentage of labeled vesicles also remained at about the same level. The low and activity-independent HRP labeling rate does not exclude the possibility of vesicle recycling but indicates that it might be only indirectly connected to the transmitter release itself.
在猫颈上神经节的突触中，研究了突触小泡数量和辣根过氧化物酶（HRP）标记的功能依赖性变化。发现只有一小部分小泡含有细胞外标记物。超强刺激（15分钟）及随后的休息（5分钟）并未导致小泡数量发生显著变化，标记小泡的百分比也基本维持在同一水平。HRP标记率低且与活性无关，这并不排除小泡循环利用的可能性，但表明它可能仅与神经递质释放本身间接相关。
