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乔纳斯·索尔克(1914 - 1995):抗击脊髓灰质炎及其他领域的先驱

Jonas Salk (1914-1995): Pioneering the Fight Against Polio and Beyond.

作者信息

Sahu Hemlata, Choudhari Sonali G, Gaidhane Abhay, Chakole Swarupa

机构信息

Department of Community Medicine, Datta Meghe Institute of Higher Education andResearch, Jawaharlal Nehru Medical College, School of Epidemiology and Public Health, Wardha, IND.

Department of Community Medicine, Datta Meghe Institute of Higher Education and Research, Jawaharlal Nehru Medical College, School of Epidemiology and Public Health, Wardha, IND.

出版信息

Cureus. 2024 Sep 18;16(9):e69681. doi: 10.7759/cureus.69681. eCollection 2024 Sep.

DOI:10.7759/cureus.69681
PMID:39429327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11489307/
Abstract

Jonas Salk (October 28, 1914 - June 23, 1995) was an American medical researcher celebrated for his pioneering work in virology, particularly the development of the first successful polio vaccine. This review highlights Salk's multifaceted talent and contributions. His research on the poliovirus led to the creation of the inactivated polio vaccine, proving that it could prevent the disease. In 1955, the discovery of the polio vaccine was a pivotal moment in the fight against poliomyelitis. Salk's contributions are celebrated in the record of medical history, highlighting his impact on modern medicine and public health. As a professor of bacteriology, preventive medicine, and experimental medicine, Salk's scientific journey, from his innovative methods to the creation and widespread use of the inactivated polio vaccine, helped eradicate polio from various parts of the world. His contributions beyond polio, such as his work on the influenza vaccine and the founding of the Salk Institute for Biological Studies, are also well known. By exploring Salk's legacy, this review examines how his work and dedication continue to influence modern medicine, public health, and science, impacting humanity.

摘要

乔纳斯·索尔克(1914年10月28日 - 1995年6月23日)是一位美国医学研究人员,因其在病毒学方面的开创性工作而闻名,尤其是首个成功的脊髓灰质炎疫苗的研发。这篇综述突出了索尔克多方面的才华和贡献。他对脊髓灰质炎病毒的研究促成了灭活脊髓灰质炎疫苗的诞生,证明其可以预防该疾病。1955年,脊髓灰质炎疫苗的发现是抗击脊髓灰质炎斗争中的一个关键时刻。索尔克的贡献在医学史上留下了浓墨重彩的一笔,凸显了他对现代医学和公共卫生的影响。作为细菌学、预防医学和实验医学教授,索尔克的科学历程,从他的创新方法到灭活脊髓灰质炎疫苗的创制及广泛应用,助力在世界多地根除了脊髓灰质炎。他在脊髓灰质炎之外的贡献,比如他在流感疫苗方面的工作以及创办索尔克生物研究所,也广为人知。通过探究索尔克的遗产,这篇综述审视了他的工作和奉献精神如何持续影响现代医学、公共卫生和科学,进而影响全人类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f14/11489307/9d27e70e98bf/cureus-0016-00000069681-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f14/11489307/9d27e70e98bf/cureus-0016-00000069681-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f14/11489307/9d27e70e98bf/cureus-0016-00000069681-i01.jpg

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本文引用的文献

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What are the barriers and facilitators to polio vaccination and eradication programs? A systematic review.脊髓灰质炎疫苗接种及根除计划的障碍与促进因素有哪些?一项系统综述。
PLOS Glob Public Health. 2022 Nov 16;2(11):e0001283. doi: 10.1371/journal.pgph.0001283. eCollection 2022.
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Jonas Salk (1914-1995): A vaccine against polio.乔纳斯·索尔克(1914 - 1995):一种抗脊髓灰质炎疫苗。
Singapore Med J. 2019 Jan;60(1):9-10. doi: 10.11622/smedj.2019002.
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A brief history of the global effort to develop a preventive HIV vaccine.全球研发预防性艾滋病疫苗努力的简史。
Vaccine. 2013 Aug 2;31(35):3502-18. doi: 10.1016/j.vaccine.2013.05.018. Epub 2013 May 21.
4
Jonas Salk. Born 28 October 1914, New York, NY; died 23 June 1995, La Jolla, CA.乔纳斯·索尔克。1914年10月28日出生于纽约州纽约市;1995年6月23日在加利福尼亚州拉霍亚去世。
Vaccine. 1995 Nov;13(16):1487. doi: 10.1016/0264-410x(95)90148-i.
5
Jonas E. Salk--discoverer of a vaccine against poliomyelitis.乔纳斯·E·索尔克——脊髓灰质炎疫苗的发现者。
Mayo Clin Proc. 1998 Dec;73(12):1176. doi: 10.4065/73.12.1176.