Massih Carine, Karam Lea, Okais Jad, Younan Tonine, Kesrouani Carole
Department of Rheumatology, Université Saint-Joseph and Hôtel-Dieu de France University Hospital, Beirut, LBN.
Department of Radiology, Université Saint-Joseph and Hôtel-Dieu de France University Hospital, Beirut, LBN.
Cureus. 2024 Sep 20;16(9):e69801. doi: 10.7759/cureus.69801. eCollection 2024 Sep.
Eosinophilic fasciitis (EF), or Shulman syndrome, is a rare connective tissue disorder characterized by symmetrical and painful swelling and with progressive thickening of the skin and soft tissues with the potential involvement of internal organs such as the pleura, pericardium, and kidneys. Patients may also present with fever, myositis, arthritis, neuropathies, and other systemic symptoms. This case report describes a unique multifocal asynchronous soft tissue involvement in Shulman syndrome in a 39-year-old patient, highlighting clinical presentation, histopathological findings, differential diagnoses, treatment modalities, and patient outcomes. Atypical migratory skin lesions must be considered in the diagnosis of EF. Timely recognition of the disease is crucial for optimal treatment and better patient outcomes.
嗜酸性筋膜炎（EF），即舒尔曼综合征，是一种罕见的结缔组织疾病，其特征为对称性疼痛性肿胀，皮肤和软组织进行性增厚，可能累及胸膜、心包和肾脏等内脏器官。患者还可能出现发热、肌炎、关节炎、神经病变及其他全身症状。本病例报告描述了一名39岁患者舒尔曼综合征中独特的多灶性异步软组织受累情况，重点介绍了临床表现、组织病理学发现、鉴别诊断、治疗方式及患者预后。在嗜酸性筋膜炎的诊断中必须考虑非典型游走性皮肤病变。及时识别该疾病对于最佳治疗和改善患者预后至关重要。
