Role of Statins in Oral and Maxillofacial Surgery: A Literature Review.

In recent years, there has been a notable increase in interest in the use of statins in oral and maxillofacial surgery. The purpose of this literature review was to look into the effectiveness of statins in this area. Using a set of keywords, a thorough search of electronic databases was carried out, including PubMed, Scopus, Web of Science, Excerpta Medica database (EMBASE), and ProQuest. The papers considered were just those published in the English language between January 2012 and January 2024. Only human studies were taken into consideration; those involving animals were not. For the final analysis that assessed the use of statins in dentistry, a total of 30 papers were chosen. The designs, sample sizes, and materials employed in the experiments varied. According to the research, statins improve bone regeneration, have antiviral and antibacterial qualities, and work well as a therapeutic adjuvant for the treatment of periodontal disease. The analysis of the literature indicates that statins may be beneficial for treating periodontal disease, promoting bone regeneration, and improving oral health in the context of oral and maxillofacial surgery. Nevertheless, more investigation is required to completely comprehend the function of statins in this domain.