Inchingolo Francesco, Inchingolo Angelo Michele, Malcangi Giuseppina, De Leonardis Nicole, Sardano Roberta, Pezzolla Carmela, de Ruvo Elisabetta, Di Venere Daniela, Palermo Andrea, Inchingolo Alessio Danilo, Corriero Alberto, Dipalma Gianna
Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
College of Medicine and Dentistry, Birmingham B4 6BN, UK.
Pharmaceuticals (Basel). 2023 Sep 16;16(9):1313. doi: 10.3390/ph16091313.
: Probiotic microorganisms, commonly used to bolster gut health, might also have benefits for dental health, according to certain studies. Probiotics (PBs) are associated with reducing cariogenic pathogens and protecting against periodontal diseases, although the exact way they function in the mouth is not fully clear. Our study aimed to explore the use of PBs to improve oral health, focusing on issues such as cavities, gum disease, bad breath, mucositis, and periimplantitis. : We utilized the Boolean keywords "Probiotics" AND "Oral health" to search the databases of PubMed, Scopus, and Web of Science. The search was restricted to English-language papers published from 1 January 2019 to 13 April 2023. : A total of 3460 articles were found through our computerized search. After removing duplicates, reviewing the papers, and determining their relevance, 12 were selected for inclusion. : Assessing how bacteria in food or dietary supplements might alter the stable oral microbiota is a complex task. Although probiotic microorganisms have been found to have proven therapeutic benefits, their application in dental health is not yet solidly backed by evidence. Further research is necessary to thoroughly understand the long-term effects of probiotic bacteria on the oral environment, including their ability to colonize and form biofilms.
根据某些研究,常用于增强肠道健康的益生菌微生物可能对牙齿健康也有益处。益生菌(PBs)与减少致龋病原体和预防牙周疾病有关,尽管它们在口腔中的确切作用方式尚不完全清楚。我们的研究旨在探索使用益生菌来改善口腔健康,重点关注龋齿、牙龈疾病、口臭、口腔黏膜炎和种植体周围炎等问题。
我们使用布尔关键词“益生菌”和“口腔健康”搜索了PubMed、Scopus和Web of Science数据库。搜索仅限于2019年1月1日至2023年4月13日发表的英文论文。
通过我们的计算机化搜索共找到3460篇文章。在去除重复项、审阅论文并确定其相关性后,选择了12篇纳入研究。
评估食物或膳食补充剂中的细菌如何改变稳定的口腔微生物群是一项复杂的任务。尽管已发现益生菌微生物具有已证实的治疗益处,但其在牙齿健康方面的应用尚未得到充分的证据支持。有必要进行进一步的研究,以全面了解益生菌对口腔环境的长期影响,包括它们定植和形成生物膜的能力。