Kubota Akira, Yamauchi Suguru, Yoshimoto Yutaro, Tsuda Kenki, Yube Yukinori, Kaji Sanae, Orita Hajime, Brock Malcolm V, Fukunaga Tetsu
Juntendo Iji Zasshi. 2024 May 24;70(3):204-213. doi: 10.14789/jmj.JMJ23-0036-OA. eCollection 2024.
The number of elderly people with stomach cancer is increasing; therefore, minimally invasive surgical treatments are required. Elderly patients have multiple comorbidities and are prone to postoperative weight loss, nutritional disorders, Postgastrectomy syndrome (PGS), and decreased quality of life (QOL). Total gastrectomy is particularly associated with these complications, although aboral-pouch creation reportedly improves the condition by compensating for lost reservoir capacity. However, there is no consensus regarding its significance. This study aimed to investigate the impact of the aboral pouch on total gastrectomy outcomes in elderly patients.
Thirty-six patients who met the eligibility criteria, defined as elderly patients aged ≥75 years, were retrospectively analyzed. The patients had undergone Roux-en-Y reconstructions with an aboral pouch in laparoscopic total gastrectomy procedures performed at Juntendo University from July 2016 to June 2022. The main outcomes were postoperative nutritional status, PGS, and QOL.
The average postoperative period was approximately 1 year (12.0 . 13.5 months, =0.536), for 14 elderly and 22 non-elderly patients, respectively. Elderly patients had more comorbidities (78.5% . 40.9%, =0.041). The outcome of nutritional status demonstrated no differences in weight-loss rate (-5.3% . -8.6%, =0.651) or prognostic nutritional status (-7.9% . -5.9%, =0.243). There was no significant difference in PGS and QOL between elderly and non-elderly patients.
Total gastrectomy with an aboral-pouch creation could be beneficial for elderly 43 patients from the perspective of postoperative nutritional status, PGS, and QOL.
老年胃癌患者数量不断增加,因此需要微创外科治疗。老年患者有多种合并症,容易出现术后体重减轻、营养紊乱、胃切除术后综合征(PGS)以及生活质量(QOL)下降。全胃切除术尤其与这些并发症相关,尽管据报道通过构建远侧袋可通过补偿失去的储存容量来改善病情。然而,其意义尚无共识。本研究旨在探讨远侧袋对老年患者全胃切除术后结局的影响。
回顾性分析了36例符合入选标准的患者,入选标准为年龄≥75岁的老年患者。这些患者在2016年7月至2022年6月于顺天堂大学进行的腹腔镜全胃切除术中接受了带远侧袋的Roux-en-Y重建术。主要结局指标为术后营养状况、PGS和QOL。
术后平均时间约为1年(分别为12.0至13.5个月,P=0.536),老年患者14例,非老年患者22例。老年患者合并症更多(78.5%对40.9%,P=0.041)。营养状况结局显示,体重减轻率(-5.3%对-8.6%,P=0.651)或预后营养状况(-7.9%对-5.9%,P=0.243)无差异。老年患者与非老年患者在PGS和QOL方面无显著差异。
从术后营养状况、PGS和QOL的角度来看,构建远侧袋的全胃切除术可能对老年患者有益。