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全胃切除术后新型吻合袋构建与单纯Roux-en-Y重建的生活质量和营养参数比较:一项前瞻性、随机、对照研究的初步结果

Comparison of quality of life and nutritional parameters after total gastrectomy and a new type of pouch construction with simple Roux-en-Y reconstruction: preliminary results of a prospective, randomized, controlled study.

作者信息

Kalmár K, Cseke L, Zámbó K, Horváth O P

机构信息

First Department of Surgery, University Medical School of Pécs, Hungary.

出版信息

Dig Dis Sci. 2001 Aug;46(8):1791-6. doi: 10.1023/a:1010634427766.

DOI:10.1023/a:1010634427766
PMID:11508685
Abstract

The aim of the study was to introduce a new type of gastric substitute, the aboral pouch, after total gastrectomy and to compare nutritional, motility, and quality of life parameters of patients with an aboral pouch to those undergoing simple Roux-en-Y reconstruction in a prospective, randomized, and controlled trial. To date 40 patients have entered the study. In 22 of them the aboral pouch was created; the remaining 18 patients with simple Roux-en-Y reconstruction served as the control group. Laboratory measurements, passage studies, lipid and carbohydrate absorption tests, and quality of life interviews were carried out as follow-up examinations. Preliminary results suggest that the aboral pouch has some advantages over simple Roux-en-Y reconstruction. Serum immunoglobulin M level and the quality of life estimated by the gastrointestinal quality of life index, yielded significantly better results in the pouch group.

摘要

本研究的目的是在全胃切除术后引入一种新型胃替代物——远侧袋,并在前瞻性、随机对照试验中比较接受远侧袋手术患者与接受单纯Roux-en-Y重建患者的营养、运动功能及生活质量参数。迄今为止,已有40例患者进入该研究。其中22例患者构建了远侧袋;其余18例行单纯Roux-en-Y重建的患者作为对照组。作为随访检查,进行了实验室测量、通过研究、脂质和碳水化合物吸收试验以及生活质量访谈。初步结果表明,远侧袋比单纯Roux-en-Y重建具有一些优势。在远侧袋组中,血清免疫球蛋白M水平以及通过胃肠道生活质量指数评估的生活质量,结果明显更好。

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