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胆汁酸的新型微生物修饰及其功能意义。

Novel microbial modifications of bile acids and their functional implications.

作者信息

Zheng Dan, Zhang Huiheng, Zheng Xiaojiao, Zhao Aihua, Jia Wei

机构信息

Center for Translational Medicine and Shanghai Key Laboratory of Diabetes Mellitus Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China.

Department of Pharmacology and Pharmacy The University of Hong Kong Hong Kong China.

出版信息

Imeta. 2024 Oct 13;3(5):e243. doi: 10.1002/imt2.243. eCollection 2024 Oct.

Abstract

This review outlines the recent discoveries of bile acids that have undergone novel microbial modifications, highlighting their biological roles and the profound implications for the development of innovative therapeutic strategies. The review aims to provide valuable insights and breakthroughs for future drug candidates in the expanding field of bile acid therapeutics.

摘要

本综述概述了近期关于经历新型微生物修饰的胆汁酸的发现,突出了它们的生物学作用以及对创新治疗策略发展的深远影响。该综述旨在为胆汁酸治疗这一不断扩展的领域中未来的候选药物提供有价值的见解和突破。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75c/11487544/2a83a8555340/IMT2-3-e243-g002.jpg

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