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单髁膝关节置换术后代谢综合征患者的术后并发症

Postoperative Complications in Patients With Metabolic Syndrome Following Unicompartmental Knee Arthroplasty.

作者信息

Schreiber Alyssa, Quan Theodore, Parel Philip, Ameigeiras Agustin, Ahmadi Sean, Wang Jeffrey, Le Jeremy D, Tabaie Sean A

机构信息

Orthopaedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.

Orthopaedic Surgery, Nationwide Children's Hospital, Columbus, USA.

出版信息

Cureus. 2024 Oct 18;16(10):e71812. doi: 10.7759/cureus.71812. eCollection 2024 Oct.

Abstract

INTRODUCTION

Metabolic syndrome is associated with increased risk of postoperative complications following various orthopedic surgeries. This study looked to identify specific postoperative complications in these patients following unicompartmental knee arthroplasty (UKA).

METHODS

Adult patients undergoing primary UKA were queried in the National Surgical Quality Improvement Program database from 2006-2019. Metabolic syndrome was defined by the simultaneous presence of hypertension, diabetes, and body mass index >30 kg/m. Two patient groups were categorized in this study: patients with metabolic syndrome and patients without metabolic syndrome. Baseline characteristics and postoperative outcomes were compared between the two cohorts with the use of bivariate and multivariate analyses.

RESULTS

In total, 10,557 patients underwent UKA. Of these, 9,511 patients (90.1%) did not have metabolic syndrome whereas 1,046 (9.9%) had metabolic syndrome. Following adjustment for potential confounding variables on multivariate analysis, metabolic syndrome patients had an increased risk of an extended length of stay greater than four days (OR 1.66; p=0.016) compared to patients without metabolic syndrome.

CONCLUSION

Metabolic syndrome was associated with an increased risk of extended length of stay greater than four days following UKA. Physicians should be prepared for this complication as well as others when discussing treatment with metabolic syndrome patients.

摘要

引言

代谢综合征与各种骨科手术后并发症风险增加相关。本研究旨在确定单髁膝关节置换术(UKA)后这些患者的特定术后并发症。

方法

在2006年至2019年的国家外科质量改进计划数据库中查询接受初次UKA的成年患者。代谢综合征的定义为同时存在高血压、糖尿病且体重指数>30kg/m²。本研究将患者分为两组:代谢综合征患者和非代谢综合征患者。使用双变量和多变量分析比较两组患者的基线特征和术后结果。

结果

共有10557例患者接受了UKA。其中,9511例患者(90.1%)没有代谢综合征,而1046例(9.9%)患有代谢综合征。在多变量分析中对潜在混杂变量进行调整后,与非代谢综合征患者相比,代谢综合征患者住院时间延长超过四天的风险增加(OR 1.66;p=0.016)。

结论

代谢综合征与UKA后住院时间延长超过四天的风险增加相关。在与代谢综合征患者讨论治疗时,医生应做好应对这种并发症及其他并发症的准备。

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Cardiovascular-Kidney-Metabolic (CKM) syndrome: A state-of-the-art review.心血管-肾脏-代谢(CKM)综合征:最新综述。
Curr Probl Cardiol. 2024 Feb;49(2):102344. doi: 10.1016/j.cpcardiol.2023.102344. Epub 2023 Dec 14.
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The Effect of Diabetes and Metabolic Syndrome on Spine Surgery Outcomes.糖尿病和代谢综合征对脊柱手术疗效的影响。
Curr Rev Musculoskelet Med. 2023 Feb;16(2):39-47. doi: 10.1007/s12178-022-09814-y. Epub 2022 Dec 28.
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The Global Epidemic of the Metabolic Syndrome.代谢综合征的全球流行。
Curr Hypertens Rep. 2018 Feb 26;20(2):12. doi: 10.1007/s11906-018-0812-z.

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