一名伯基特淋巴瘤患者骨髓穿刺阴性标本中的8号与14号染色体易位

8;14 chromosome translocation in a negative bone marrow aspirate from a patient with Burkitt's lymphoma.

作者信息

Richardson L A, Dickerman J D

出版信息

Cancer. 1986 Feb 15;57(4):761-3. doi: 10.1002/1097-0142(19860215)57:4<761::aid-cncr2820570413>3.0.co;2-c.

DOI:10.1002/1097-0142(19860215)57:4<761::aid-cncr2820570413>3.0.co;2-c

Abstract

A patient with Burkitt's lymphoma is described who, on presentation, had a bone marrow aspirate which did not show abnormal cells. Cells from the bone marrow were cultured and an 8;14 chromosome translocation was identified. This finding allowed us to upgrade the stage of disease from III to IV with therapeutic as well as prognostic implications.

摘要

报告了一名伯基特淋巴瘤患者，初诊时骨髓穿刺未发现异常细胞。对骨髓细胞进行培养后，发现了8号与14号染色体易位。这一发现使我们能够将疾病分期从III期提升至IV期，这对治疗和预后均有影响。