EBV 阴性的伴有伯基特样细胞的 B 细胞急性淋巴细胞白血病中的 8;14 相互易位
Reciprocal 8;14 translocation in EBV-negative B-cell acute lymphocytic leukemia with Burkitt-type cells.
作者信息
Mitelman F, Andersson-Anvret M, Brandt L, Catovsky D, Klein G, Manolov G, Manolova Y, Mark-Vendel E, Nilsson P G
出版信息
Int J Cancer. 1979 Jul 15;24(1):27-33. doi: 10.1002/ijc.2910240106.
PMID:90020
Abstract
A cytogenetic study, including prophase-prometaphase chromosome analysis, of a patient with EBV-genome-negative acute lymphocytic leukemia of B-cell type with Burkitt-type cells is presented. All bone-marrow mitoses examined had a 14q+ marker chromosome which was identified as a reciprocal 8;14 translocation of exactly the same type as in Burkitt's lymphoma.
摘要
本文报告了对一名患有B细胞型EBV基因组阴性急性淋巴细胞白血病且伴有伯基特型细胞的患者进行的细胞遗传学研究，包括前期-前中期染色体分析。所有检查的骨髓有丝分裂均有一条14q+标记染色体，该染色体被鉴定为与伯基特淋巴瘤中完全相同类型的8号与14号染色体相互易位。
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