三例具有相同易位t(1;3)的白血病前期骨髓发育异常疾病
Three cases of preleukemic myelodysplastic disorders with the same translocation t(1;3).
作者信息
Viguie F, Marie J P, Poler F, Bernadou A
出版信息
Cancer Genet Cytogenet. 1986 Jan 15;19(3-4):213-8. doi: 10.1016/0165-4608(86)90049-x.
PMID:3943045
Abstract
The same translocation, t(1;3)(p36;q21), was observed in three patients with a preleukemic syndrome presenting as a myelodysplastic disorder. It was the only chromosomal abnormality in two patients; and the third patient had 12p- and 15q- as additional abnormalities. The three cases evolved into acute nonlymphocytic leukemia.
摘要
在三名表现为骨髓增生异常疾病的白血病前期综合征患者中观察到相同的易位，即t(1;3)(p36;q21)。在两名患者中，这是唯一的染色体异常；第三名患者还存在12号染色体短臂缺失和15号染色体长臂缺失等其他异常。这三例均发展为急性非淋巴细胞白血病。
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