用锌/铜还原芳香族硝基化合物。N-乙酰氧基-N-乙酰基芳胺的一种新合成方法。
The reduction of aromatic nitro compounds with Zn/Cu. A new synthesis of N-acetoxy-N-acetyl-arylamines.
作者信息
Franz R, Neumann H G
出版信息
Carcinogenesis. 1986 Jan;7(1):183-4. doi: 10.1093/carcin/7.1.183.
PMID:3943141
Abstract
A new and simple synthesis is described for N-acetoxy-N-acetyl-derivatives of trans-4-aminostilbene, 2-aminofluorene and 2-aminophenanthrene using a Zn/Cu-couple for the reduction of the nitro-aromatics. This method produces good yields and should also be applicable for other N-aryl-compounds. It can also be used for the reduction of nitro-aromatics to the respective arylamines and arylamides.
摘要
描述了一种新的简单合成方法，用于制备反式-4-氨基芪、2-氨基芴和2-氨基菲的N-乙酰氧基-N-乙酰衍生物，该方法使用锌/铜偶对还原硝基芳烃。此方法产率良好，也应适用于其他N-芳基化合物。它还可用于将硝基芳烃还原为相应的芳胺和芳酰胺。
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