Li Jiaqing, Niu Yang, Yuan Ling, Jiang Wenjie, Jiao Taiqiang, Dou Hongli, Nan Yi
Ningxia Medical University Key Laboratory of Ningxia Minority Medicine Modernization Ministry of Education, Yinchuan, China.
Traditional Chinese Medicine College, Ningxia Medical University, Yinchuan, China.
J Med Food. 2024 Dec;27(12):1145-1157. doi: 10.1089/jmf.2024.k.0057. Epub 2024 Oct 21.
Gastrointestinal tumors have a major impact on human life expectancy and quality of life and are a major cause of personal and social hygiene stress. Gastrointestinal tumors are the main cause of cancer-related death, and the main treatment methods are surgery, radiotherapy, and chemotherapy. However, they also cause great damage to the body and have a poor prognosis after surgery. Therefore, we urgently need safe and effective drugs to intervene in gastrointestinal tumors. In recent years, Traditional Chinese Medicine has been widely used in tumor treatment as a complementary and alternative therapy. is one of the main herbal medicines with tonic effect and one of the important components of many antitumor herbal compounds. Astragalus polysaccharides, saponins, and flavonoids are the main active components of Astragalus, all of which have antitumor effects. In this article, we studied the mechanism of action of Astragalus and its active ingredients in the intervention of gastrointestinal tumors in recent years and suggested a new approach for the study of Astragalus intervention in gastrointestinal tumors from the perspective of the homology of medicine and food.
胃肠道肿瘤对人类预期寿命和生活质量有重大影响，是个人和社会卫生压力的主要原因。胃肠道肿瘤是癌症相关死亡的主要原因，主要治疗方法是手术、放疗和化疗。然而，它们也会对身体造成巨大损害，术后预后较差。因此，我们迫切需要安全有效的药物来干预胃肠道肿瘤。近年来，中医药作为一种补充和替代疗法在肿瘤治疗中得到广泛应用。黄芪是具有滋补作用的主要草药之一，也是许多抗肿瘤草药化合物的重要组成部分。黄芪多糖、皂苷和黄酮类化合物是黄芪的主要活性成分，均具有抗肿瘤作用。在本文中，我们研究了近年来黄芪及其活性成分在干预胃肠道肿瘤中的作用机制，并从药食同源的角度提出了黄芪干预胃肠道肿瘤研究的新途径。
