Keskinis Christodoulos, Panagoutsos Stylianos, Kyriklidou Parthena, Pateinakis Panagiotis, Manou Eleni, Soilemezi Eleni, Papadopoulou Dorothea, Passadakis Ploumis
Department of Nephrology, Papageorgiou Hospital, Thessaloniki, Greece.
Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
J Ultrasound. 2025 Mar;28(1):89-99. doi: 10.1007/s40477-024-00964-y. Epub 2024 Oct 21.
Hypervolemia remains a problem in hemodialysis patients and is associated with hypertension, cardiovascular events and mortality. Lung Ultrasound (LUS) is a technique that detects hypervolemia via 4 different protocols depending on the number of sites checked on the chest wall. It has not been established which protocol should be preferred in the literature.
This study included 68 hemodialysis patients from one Dialysis Unit. All the patients underwent LUS with every single protocol 30 min before and after the end of the middle-week dialysis session by a nephrology trainee. Patients' ideal weight was modified based on daily clinical practice rather than ultrasound findings.
Seventeen patients (25%) had ultrasound findings compatible with hypervolemia before the dialysis session, while eleven patients (16.2%) had still pulmonary congestion after the end of the session. These findings were similar to the number of patients considered hyperhydrated based on clinical criteria (10 patients). The rest protocols (8-zone, 6-zone and 4-zone protocol) considered fewer patients as hypervolemic.
The 28-zone protocol can effectively detect hypervolemia and even classify the degree of it, although It is a time-consuming method. However, the other protocols can detect the hypervolemia in hemodialysis patients only when severe lung congestion exists. Their usefulness is limited in daily clinical practice in hemodialysis patients. More studies should be carried out for further and more reliable conclusions.
血容量过多仍是血液透析患者面临的一个问题,且与高血压、心血管事件及死亡率相关。肺部超声(LUS)是一种通过4种不同方案来检测血容量过多的技术,这取决于在胸壁上检查的部位数量。文献中尚未确定哪种方案更可取。
本研究纳入了来自一个透析单元的68例血液透析患者。所有患者在周中透析 session 结束前30分钟和结束后,由一名肾科实习医生采用每种方案进行肺部超声检查。患者的理想体重根据日常临床实践而非超声检查结果进行调整。
17例患者(25%)在透析 session 前超声检查结果与血容量过多相符,而11例患者(16.2%)在 session 结束后仍有肺部充血。这些结果与根据临床标准判定为水合过多的患者数量(10例)相似。其余方案(8区、6区和4区方案)判定为血容量过多的患者较少。
28区方案能有效检测血容量过多,甚至能对其程度进行分类,尽管这是一种耗时的方法。然而,其他方案仅在存在严重肺部充血时才能检测出血液透析患者的血容量过多。它们在血液透析患者的日常临床实践中的实用性有限。需要开展更多研究以得出进一步且更可靠的结论。