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三尖瓣反流的多模态影像学管理。

Multimodality Imaging in the Management of Tricuspid Valve Regurgitation.

机构信息

Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zurich, Switzerland.

出版信息

Echocardiography. 2024 Oct;41(10):e15960. doi: 10.1111/echo.15960.

Abstract

Approximately 5% of elderly patients suffer from moderate or severe tricuspid valve regurgitation, which is an independent predictor of high morbidity and mortality. Surgical treatment of isolated tricuspid valve regurgitation has been associated with elevated fatality rate, leading to a growing interest in minimal invasive, transcatheter-based therapies such as transcatheter edge-to-edge repair and transcatheter valve replacement. Nevertheless, despite high procedural efficacy and safety of transcatheter-based therapies, a number of challenges limit their rapid adoption in routine clinical practice. In particular, the wide range of transcatheter approaches to address the significant variability in tricuspid valve pathology challenges the reproducibility of clinical outcomes. Multimodality imaging is pivotal for grading the regurgitation severity, determining the underlying pathology, assessing RV function and pulmonary pressures, identifying concomitant cardiac disease, and selecting the most beneficial treatment modality and access. This article reviews the role of different imaging modalities in guiding the management of patients with significant tricuspid valve regurgitation.

摘要

约 5%的老年患者患有中重度三尖瓣反流,这是高发病率和死亡率的独立预测因素。孤立性三尖瓣反流的手术治疗与病死率升高相关,这促使人们对微创、经导管治疗方法产生了越来越大的兴趣,如经导管瓣环成形术和经导管瓣膜置换术。然而,尽管经导管治疗方法具有较高的程序疗效和安全性,但仍存在一些挑战,限制了它们在常规临床实践中的快速应用。特别是,经导管治疗方法广泛应用于解决三尖瓣病变的显著变异性,这对临床结果的可重复性提出了挑战。多模态成像对于评估反流严重程度、确定潜在病理、评估 RV 功能和肺动脉压、识别并存的心脏疾病以及选择最有益的治疗方式和途径至关重要。本文综述了不同影像学方法在指导重度三尖瓣反流患者管理中的作用。

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