来自人类骨髓的正成红细胞和巨成红细胞中的铁蛋白含量。
The ferritin content of normoblasts and megaloblasts from human bone marrow.
作者信息
Hodgetts J, Peters S W, Hoy T G, Jacobs A
出版信息
Clin Sci (Lond). 1986 Jan;70(1):47-51. doi: 10.1042/cs0700047.
PMID:3943277
Abstract
Erythroblasts were enriched from human bone marrow samples and fractionated on Percoll gradients according to maturity. Heart-type and spleen-type ferritin was measured in each fraction by an immunoradiometric assay. In normal marrow, heart-type ferritin content was higher in the early erythroblast fractions and fell with maturation. Spleen-type ferritin content showed no such consistent change. Megaloblastic erythroblasts had a significantly higher ferritin content.
摘要
从人骨髓样本中富集有核红细胞，并根据成熟度在Percoll梯度上进行分级分离。通过免疫放射分析测定每个级分中的心脏型和脾脏型铁蛋白。在正常骨髓中，早期有核红细胞级分中的心脏型铁蛋白含量较高，并随着成熟而下降。脾脏型铁蛋白含量没有这种一致的变化。巨幼红细胞的铁蛋白含量明显更高。
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