Gurevitch M J, Van Dyke J, Young E S, Jackson K
Chest. 1986 Feb;89(2):211-3. doi: 10.1378/chest.89.2.211.
Two patients with the adult respiratory distress syndrome (ARDS) were placed on pressure-controlled inverse-ratio ventilation (IRV) when their condition deteriorated despite optimal treatment with intermittent mandatory ventilation and positive end-expiratory pressure. In the first case, high peak airway pressure was reduced by 50 percent with the institution of IRV. In the second, refractory hypoxemia was eliminated by using an inspiratory-to-expiratory ratio of 4:1. These cases show that IRV may offer certain advantages in the treatment of severe ARDS.
两名患有成人呼吸窘迫综合征（ARDS）的患者，尽管采用间歇强制通气和呼气末正压进行了最佳治疗，但病情仍恶化，随后接受了压力控制反比通气（IRV）治疗。在第一个病例中，采用IRV后，气道峰压降低了50%。在第二个病例中，通过使用4:1的吸气与呼气比消除了难治性低氧血症。这些病例表明，IRV在治疗重症ARDS方面可能具有某些优势。
