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暴露于绿色空间与中国人群心电图异常的关联:一项全国性纵向研究。

Association between exposure to greenspace and ECG abnormalities in China: a nationwide longitudinal study.

机构信息

School of Health Policy and Management, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.

Department of Cardiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.

出版信息

BMC Public Health. 2024 Oct 21;24(1):2914. doi: 10.1186/s12889-024-20352-9.

Abstract

BACKGROUND

Greenspace is an important modifiable environmental factor that is associated with health and well-being. Although previous research has shown that exposure to greenspace is beneficial for cardiovascular diseases, studies have rarely focused on early subclinical health outcomes such as electrocardiogram (ECG) abnormality.

METHODS

We developed a longitudinal study using data from the China National Stroke Screening Survey (2013-2019). Monthly exposure to greenspace was assessed by the Normalized Difference Vegetation Index (NDVI) values. ECG abnormality was diagnosed by physicians based on the results of the 12-lead electrocardiogram. We used fixed-effects logistic regression with participant-specific intercepts to estimate the association between exposure to greenspace and ECG abnormalities.

RESULTS

A total of 132,108 visits from 61,029 participants with ≥ 2 ECG measurements were included. At baseline, the lag-1 month average NDVI value was 0.29 (SD = 0.15). In the fully adjusted model, per 0.1-unit increment in lag-1 month average NDVI value was associated with a 3.0% (95% CI -1.6 ∼ 7.4%) decreased risk of ECG abnormality. In urban areas, the decreased risk associated with per 0.1-unit increment in NDVI was 14.81% (95% CI 9.38 ∼ 19.92%).

CONCLUSION

Our study found that higher exposure to greenspace was associated with a decreased risk of ECG abnormality, especially in urban areas. Our findings suggested that monthly exposure to greenspace might be beneficial to cardiovascular health, and greenspace provision and maintenance could be considered an important public health intervention in urban planning.

摘要

背景

绿地是一个重要的可调节环境因素,与健康和幸福感有关。尽管先前的研究表明,接触绿地有益于心血管疾病,但很少有研究关注早期亚临床健康结果,如心电图(ECG)异常。

方法

我们使用中国国家卒中筛查调查(2013-2019 年)的数据开展了一项纵向研究。通过归一化差异植被指数(NDVI)值评估每月绿地暴露情况。心电图异常由医生根据 12 导联心电图的结果进行诊断。我们使用具有参与者特定截距的固定效应逻辑回归来估计绿地暴露与心电图异常之间的关联。

结果

共纳入 61029 名参与者的 132108 次就诊,这些参与者至少有 2 次心电图测量。在基线时,滞后 1 个月的平均 NDVI 值为 0.29(SD=0.15)。在完全调整的模型中,滞后 1 个月平均 NDVI 值每增加 0.1 个单位,心电图异常的风险降低 3.0%(95%CI:-1.67.4%)。在城市地区,NDVI 每增加 0.1 个单位,与风险降低相关的幅度为 14.81%(95%CI:9.3819.92%)。

结论

我们的研究发现,较高的绿地暴露与心电图异常风险降低有关,尤其是在城市地区。我们的研究结果表明,每月接触绿地可能有益于心血管健康,在城市规划中,绿地供应和维护可以被视为一项重要的公共卫生干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0b0/11494809/c5648d5661fe/12889_2024_20352_Fig1_HTML.jpg

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