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利用磁共振成像检查4至9岁儿童腭咽结构的年龄、性别和种族特征。

Examining age, sex, and race characteristics of velopharyngeal structures in 4- to 9-year old children using magnetic resonance imaging.

作者信息

Perry Jamie L, Kollara Lakshmi, Kuehn David P, Sutton Bradley P, Fang Xiangming

机构信息

Department of Communication Sciences and Disorders, East Carolina University, Greenville, NC, USA.

Department of Speech and Hearing Science, University of Illinois at Urbana-Champaign, Champaign, IL, USA.

出版信息

Cleft Palate Craniofac J. 2018 Jan;55(1):21-34. doi: 10.1177/1055665617718549. Epub 2017 Dec 14.

Abstract

OBJECTIVE

The purpose of this study was to quantify the growth of the various craniofacial and velopharyngeal structures and examine sex and race effects.

METHODS

Eight-five healthy children (53 White and 32 Black) with normal velopharyngeal anatomy between 4 and 9 years of age who met the inclusion criteria and successfully completed the MRI scans were included in the study.

RESULTS

Developmental normative mean values for selected craniometric and velopharyngeal variables by race and sex are reported. Cranial variables (face height, nasion to sella, sella to basion, palate height, palate width) and velopharyngeal variables (levator muscle length, angle of origin, sagittal angle, velar length, velar thickness, velar knee to posterior pharyngeal wall, and posterior nasal spine to levator muscle) demonstrated a trend toward a decrease in angle measures and increase in linear measures as age increased (with the exception of PNS to levator muscle). Only hard palate width and levator muscle length showed a significant sex effect. However, two cranial and six velopharyngeal variables showed a significant race effect. The interactions between sex, race, and age were not statistically significant across all variables, with the exception of posterior nasal spine to posterior pharyngeal wall.

CONCLUSION

Findings established a large age and race-specific normative reference for craniometiric and velopharyngeal variables. Data reveal minimal sexual dimorphism variables used in the present study; however, significant racial effects were observed.

摘要

目的

本研究旨在量化各种颅面和腭咽结构的生长情况,并研究性别和种族的影响。

方法

85名4至9岁腭咽解剖结构正常、符合纳入标准并成功完成MRI扫描的健康儿童(53名白人、32名黑人)被纳入研究。

结果

报告了按种族和性别划分的选定颅骨测量和腭咽变量的发育标准均值。颅骨变量(面高、鼻根至蝶鞍、蝶鞍至颅底、腭高、腭宽)和腭咽变量(提肌长度、起始角度、矢状角、腭帆长度、腭帆厚度、腭帆转折处至咽后壁、后鼻棘至提肌)显示,随着年龄增长,角度测量值有减小趋势,线性测量值有增加趋势(后鼻棘至提肌除外)。只有硬腭宽度和提肌长度显示出显著的性别效应。然而,两个颅骨变量和六个腭咽变量显示出显著的种族效应。除后鼻棘至咽后壁外,性别、种族和年龄之间的交互作用在所有变量中均无统计学意义。

结论

研究结果为颅骨测量和腭咽变量建立了一个针对年龄和种族的大型标准参考。数据显示本研究中使用的性别二态性变量极小;然而,观察到了显著的种族效应。

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