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[去铁胺持续皮下输注期间纯合子β地中海贫血患者的纵向生长情况]

[Longitudinal growth of patients with homozygote beta-thalassemia during continuous subcutaneous infusion of deferoxamine].

作者信息

Krüger N, Stubbe P, Tillmann W, Schröter W

出版信息

Dtsch Med Wochenschr. 1986 Jan 31;111(5):176-81. doi: 10.1055/s-2008-1068422.

Abstract

Subcutaneous continuous infusions of deferoxamine were administered to 28 children with thalassaemia major. Longitudinal growth beyond the eleventh year was favourably influenced. The normal growth spurt during puberty was not demonstrable in six patients (three boys and three girls) during their puberty. Taking into account standard height allowing for parents' height, prospective final height and ethnic origin, the treatment favourably influenced longitudinal growth in 26 of the 28 children.

摘要

对28名重型地中海贫血患儿进行了皮下持续输注去铁胺治疗。11岁以后的纵向生长受到了积极影响。6名患者(3名男孩和3名女孩)在青春期未出现正常的生长突增。综合考虑根据父母身高得出的标准身高、预期最终身高和种族来源,该治疗对28名患儿中的26名的纵向生长产生了积极影响。

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